Xie Hong-Yu, Yuan Ai-Hong, Yang Jun
Department of Acupuncture-Moxibustion and Rehabilitation, First Affiliated Hospital of Anhui University of CM, Hefei 230031, China.
Zhongguo Zhen Jiu. 2020 Dec 12;40(12):1286-90. doi: 10.13703/j.0255-2930.20191217-0004.
To observe the effect of moxibustion on cognitive function in patients with cognitive decline of type 2 diabetes mellitus (T2DM).
A total of 47 patients with cognitive decline of T2DM were randomized into an observation group (24 cases, 4 cases dropped off ) and a control group (23 cases, 3 cases dropped off ). Conventional hypoglycemic intervention was adopted in the control group. On the basis of the treatment in the control group, moxibustion (moxibustion for removing stasis and clearing collaterals) was applied at Baihui (GV 20), Dazhui (GV 14), Shenting (GV 24), once every 2 days, 4 weeks were as one course, totally 3 courses were required. Before and after treatment, scores of auditory verbal learning test (AVLT), complex figure test (CFT), Montreal cognitive assessment (MoCA) and trail making test-A (TMT-A) were observed in the both groups, and the clinical effective rates were compared.
After treatment, the scores of immediate memory and delayed memory of AVLT in the observation group were higher than those before treatment and those in the control group (<0.05). After treatment, the scores of visual space and executive function, delayed memory, attention and orientation of MoCA in the observation group were higher than those before treatment and those in the control group (<0.05). The effective rate was 85.0% (17/20) in the observation group, which was superior to 10.0% (2/20) in the control group (<0.05).
moxibustion has a definite effect on cognitive decline of type 2 diabetes mellitus.
观察艾灸对2型糖尿病(T2DM)认知功能减退患者认知功能的影响。
将47例T2DM认知功能减退患者随机分为观察组(24例,脱落4例)和对照组(23例,脱落3例)。对照组采用常规降糖干预。在对照组治疗的基础上,于百会(GV 20)、大椎(GV 14)、神庭(GV 24)进行艾灸(化瘀通络灸),每2天1次,4周为1个疗程,共需3个疗程。观察两组治疗前后听觉词语学习测验(AVLT)、复杂图形测验(CFT)、蒙特利尔认知评估量表(MoCA)及连线测验-A(TMT-A)评分,并比较临床有效率。
治疗后,观察组AVLT的即刻记忆和延迟记忆评分高于治疗前及对照组(P<0.05)。治疗后,观察组MoCA的视觉空间与执行功能、延迟记忆、注意力及定向力评分高于治疗前及对照组(P<0.05)。观察组有效率为85.0%(17/20),优于对照组的10.0%(2/20)(P<0.05)。
艾灸对2型糖尿病认知功能减退有确切疗效。