嗅觉功能障碍与慢性鼻-鼻窦炎。
Olfactory Dysfunction and Chronic Rhinosinusitis.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, 601 North Caroline Street, 6th floor, Suite 6164, Baltimore, MD 21287, USA.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, 601 North Caroline Street, 6th floor, Suite 6164, Baltimore, MD 21287, USA.
出版信息
Immunol Allergy Clin North Am. 2020 May;40(2):223-232. doi: 10.1016/j.iac.2019.12.013. Epub 2020 Jan 16.
Olfactory dysfunction (OD) is one of the cardinal symptoms of chronic rhinosinusitis (CRS), and its prevalence ranges from 60% to 80% in patients with CRS. It is much more common in CRS with nasal polyposis patients compared to CRS without nasal polyposis. Decreased olfactory function is associated with significant decreases in patient-reported quality of life (QOL), and notably, depression and the enjoyment of food. Objective measures can help detail the degree of OD, whereas subjective measures can help to determine in the impact on patient. There is variable treatment response to OD with both medical and surgical therapies.
嗅觉功能障碍（OD）是慢性鼻-鼻窦炎（CRS）的主要症状之一，其在 CRS 患者中的患病率为 60%至 80%。与无鼻息肉的 CRS 相比，伴有鼻息肉的 CRS 患者更为常见。嗅觉功能下降与患者报告的生活质量（QOL）显著下降有关，特别是与抑郁和食物享受有关。客观测量有助于详细说明 OD 的程度，而主观测量有助于确定对患者的影响。无论是药物治疗还是手术治疗，OD 的治疗反应都存在差异。
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