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铅及铅锌联合处理后大鼠对硫胺素、葡萄糖和钠的肠道吸收

Intestinal absorption of thiamine, glucose and sodium in rats after lead and joint lead-zinc treatment.

作者信息

Dolezych S

机构信息

Chair of Human and Animal Physiology, Silesian University, Katowice.

出版信息

Acta Physiol Pol. 1988 May-Jun;39(3):195-201.

PMID:3227869
Abstract

Intestinal absorption of thiamine, glucose and sodium was studied by perfusion method in situ in control rats, in rats subchronically poisoned with lead and in rats subchronically poisoned with lead and zinc administered jointly. In lead poisoned rats absorption of the investigated substances was increased. In lead and zinc poisoned rats intestinal absorption was not elevated. This seems to indicate that interaction between lead and zinc was antagonistic also when the metals were administered parenterally.

摘要

通过原位灌注法研究了对照大鼠、亚慢性铅中毒大鼠以及联合给予铅和锌的亚慢性中毒大鼠对硫胺素、葡萄糖和钠的肠道吸收情况。在铅中毒大鼠中,所研究物质的吸收增加。在铅和锌中毒大鼠中,肠道吸收并未升高。这似乎表明,即使通过非肠道途径给予铅和锌,它们之间的相互作用也是拮抗的。

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