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激素对假孕中期大鼠子宫-卵巢血流分布的影响。

Hormonal influence on utero-ovarian blood flow distribution in the mid-luteal pseudopregnant rat.

作者信息

Gåfvels M, Olofsson J, Norjavaara E, Selstam G

机构信息

Department of Physiology, University of Umeå, Sweden.

出版信息

Acta Physiol Scand. 1988 Mar;132(3):329-34. doi: 10.1111/j.1748-1716.1988.tb08336.x.

DOI:10.1111/j.1748-1716.1988.tb08336.x
PMID:3227878
Abstract

Uterine and ovarian blood flows and ovarian fractional perfusion were measured in adult rats anaesthetized with sodium pentobarbital i.p. on day 6 of pseudopregnancy, by using radioactive microspheres. Fifty i.u. human chorionic gonadotropin (hCG) was found to increase the fractional perfusion of the ovary, and this was at least partially accomplished at the expense of the uterine blood flow, since this was reduced. Noradrenaline (NA) infusion (2 nmol min-1) reduced ovarian as well as uterine blood flow acutely. After 20 min of NA infusion (2 nmol min-1), however, ovarian blood flow and fractional perfusion were increased, while no significant effect was seen for uterine blood flow. Antidiuretic hormone (ADH) in a 20-min infusion (1 nmol min-1) markedly reduced ovarian and uterine blood flows.

摘要

在假孕第6天,对腹腔注射戊巴比妥钠麻醉的成年大鼠,使用放射性微球测量子宫和卵巢血流以及卵巢局部灌注。发现50国际单位的人绒毛膜促性腺激素(hCG)可增加卵巢的局部灌注,且这至少部分是以子宫血流减少为代价实现的,因为子宫血流减少了。去甲肾上腺素(NA)输注(2 nmol·min⁻¹)可急性降低卵巢和子宫血流。然而,在输注NA(2 nmol·min⁻¹)20分钟后,卵巢血流和局部灌注增加,而子宫血流未见明显变化。抗利尿激素(ADH)在20分钟输注(1 nmol·min⁻¹)时可显著降低卵巢和子宫血流。

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Hormonal influence on utero-ovarian blood flow distribution in the mid-luteal pseudopregnant rat.激素对假孕中期大鼠子宫-卵巢血流分布的影响。
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