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Astrocyte-derived ATP modulates depressive-like behaviors.星形胶质细胞衍生的 ATP 调节抑郁样行为。
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本文引用的文献

1
Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model.抑郁症认知和心理机制中的神经可塑性：一种综合模型。
Mol Psychiatry. 2020 Mar;25(3):530-543. doi: 10.1038/s41380-019-0615-x. Epub 2019 Dec 4.
2
Astroglia-Derived ATP Modulates CNS Neuronal Circuits.星形胶质细胞衍生的 ATP 调节中枢神经系统神经元回路。
Trends Neurosci. 2019 Dec;42(12):885-898. doi: 10.1016/j.tins.2019.09.006. Epub 2019 Nov 5.
3
Optogenetic and chemogenetic insights into the neurocircuitry of depression-like behaviour: A systematic review.光遗传学和化遗传学对抑郁症样行为神经回路的研究进展：系统综述。
Eur J Neurosci. 2021 Jan;53(1):9-38. doi: 10.1111/ejn.14603. Epub 2019 Nov 11.
4
P2X7 Receptor Signaling in Stress and Depression.P2X7 受体在应激和抑郁中的信号转导。
Int J Mol Sci. 2019 Jun 6;20(11):2778. doi: 10.3390/ijms20112778.
5
Emerging role of the P2X7-NLRP3-IL1β pathway in mood disorders.P2X7-NLRP3-IL1β 通路在心境障碍中的新兴作用。
Psychoneuroendocrinology. 2018 Dec;98:95-100. doi: 10.1016/j.psyneuen.2018.08.015. Epub 2018 Aug 14.
6
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes.抗抑郁药氟西汀通过星形胶质细胞发挥其治疗作用。
EBioMedicine. 2018 Jun;32:72-83. doi: 10.1016/j.ebiom.2018.05.036. Epub 2018 Jun 8.
7
Pannexin-1 channel dysfunction in the medial prefrontal cortex mediates depressive-like behaviors induced by chronic social defeat stress and administration of mefloquine in mice.内侧前额叶皮层的 P2X7 通道功能障碍介导慢性社会挫败应激和甲氟喹给药诱导的小鼠抑郁样行为。
Neuropharmacology. 2018 Jul 15;137:256-267. doi: 10.1016/j.neuropharm.2017.12.004. Epub 2017 Dec 6.
8
Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors.Calhm2 调控星形胶质细胞 ATP 的释放，进而参与抑郁样行为的发生。
Mol Psychiatry. 2018 Apr;23(4):883-891. doi: 10.1038/mp.2017.229. Epub 2017 Nov 28.
9
Gap junction channels as potential targets for the treatment of major depressive disorder.缝隙连接通道作为治疗重度抑郁症的潜在靶点。
Psychopharmacology (Berl). 2018 Jan;235(1):1-12. doi: 10.1007/s00213-017-4782-7. Epub 2017 Nov 25.
10
P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression.P2X7 受体在抑郁的习得性无助模型中驱动脊柱突触可塑性。
Int J Neuropsychopharmacol. 2017 Oct 1;20(10):813-822. doi: 10.1093/ijnp/pyx046.

Impaired ATP Release from Brain Astrocytes May be a Cause of Major Depression.

作者信息

Illes Peter, Rubini Patrizia, Yin Haiyan, Tang Yong

机构信息

Rudolf Boehm Institute for Pharmacology and Toxicology, University of Leipzig, 04107, Leipzig, Germany.

School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

出版信息

Neurosci Bull. 2020 Nov;36(11):1281-1284. doi: 10.1007/s12264-020-00494-7. Epub 2020 Apr 11.

DOI:10.1007/s12264-020-00494-7
PMID:32279193
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7674522/
Abstract
摘要