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实施两项针对服务不足女性的 HPV 自我采样的随机实用临床试验:挑战和经验教训。

Implementing Two Randomized Pragmatic Trials of HPV Self-sampling among Underserved Women: Challenges and Lessons Learned.

出版信息

Prog Community Health Partnersh. 2020;14(1):55-62. doi: 10.1353/cpr.2020.0008.

DOI:10.1353/cpr.2020.0008
PMID:32280123
Abstract

BACKGROUND

Haitian and Hispanic immigrant women experience substantial disparities in cervical cancer screening. Recently, our team completed two randomized trials of human papillomavirus (HPV) self-sampling as a cervical cancer screening strategy among Haitian and Hispanic women, using a community-based participatory research (CBPR) approach.

OBJECTIVE

To reflect on lessons learned in the process of completing two large randomized cancer screening trials within underserved communities.

METHODS

Haitian and Hispanic women were randomized to HPV self-sampling versus navigation to Pap smear versus standard cervical cancer screening education in the first trial, and HPV self-sampling delivered in-person versus via mail in the second trial.

LESSONS LEARNED

During the two trials, our team encountered several challenges. The lessons learned from these challenges allowed for the strengthening of our community partnerships, study procedures, and our ability to conduct CBPR within an academic setting.

CONCLUSIONS

Lessons learned from our trials may be useful to other researchers engaging in CBPR within underserved communities.

摘要

背景

海地和西班牙裔移民妇女在宫颈癌筛查方面存在显著差异。最近,我们的团队完成了两项关于人乳头瘤病毒(HPV)自我采样的随机试验,这是一种针对海地和西班牙裔妇女的宫颈癌筛查策略,采用了基于社区的参与式研究(CBPR)方法。

目的

反思在服务不足社区中完成两项大型癌症筛查随机试验的过程中学到的经验教训。

方法

在第一项试验中,海地和西班牙裔妇女被随机分配接受 HPV 自我采样、导航至巴氏涂片检查或标准宫颈癌筛查教育,在第二项试验中,接受 HPV 自我采样的方式为亲自进行或通过邮件进行。

经验教训

在这两项试验中,我们的团队遇到了一些挑战。从这些挑战中吸取的经验教训加强了我们的社区伙伴关系、研究程序以及我们在学术环境中开展 CBPR 的能力。

结论

从我们的试验中吸取的经验教训可能对其他在服务不足的社区中从事 CBPR 的研究人员有用。

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