软性输尿管镜联合钬激光碎石术致全身炎症反应综合征的危险因素。
Risk Factors for Systemic Inflammatory Response Syndrome Induced by Flexible Ureteroscope Combined with Holmium Laser Lithotripsy.
机构信息
Department of Urology, Dongguan People's Hospital, Dongguan, 523059 Guangdong, China.
Xinxiang Medical University, Xinxiang, 453003 Henan, China.
出版信息
Biomed Res Int. 2020 Mar 21;2020:6842479. doi: 10.1155/2020/6842479. eCollection 2020.
OBJECTIVE
To investigate the risk factors of systemic inflammatory response syndrome (SIRS) induced by flexible ureteroscope combined with Holmium laser lithotripsy. . The clinical data from 216 consecutive patients who had undergone flexible ureteroscope combined with Holmium laser lithotripsy between August 2015 and May 2019 were retrospectively analyzed. To identify the risk factors of systemic inflammatory response syndrome induced by flexible ureteroscope combined with Holmium laser lithotripsy, the cases were divided into two groups according to whether they developed postoperative SIRS: SIRS group (21 cases) and non-SIRS group (195 cases). Age, gender, body mass index, stone size, surgery time, stone location, hydronephrosis, urine culture, hospital stay, stone-free rate, ureteral access sheath, and diabetes mellitus were collected. Univariate analysis was performed to calculate the potential factors. In order to determine the independence of the various factors, factors that potentially contributed to SIRS were compared between the SIRS group and the non-SIRS group. Furthermore, multivariate logistic regression analysis was used to identify the risk factors of systemic inflammatory response syndrome induced by flexible ureteroscopic lithotripsy.
RESULTS
All patients were successfully treated with flexible ureteroscopic lithotripsy. The incidence of SIRS after flexible ureteroscopic lithotripsy was 9.7%. The univariate analysis demonstrated the potential risk factors of systemic inflammatory response syndrome induced by flexible ureteroscopic lithotripsy were stone size ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time ( = 0.002), surgery time (.
CONCLUSIONS
Stone size, surgery time, urine culture, and ureteral access sheath are independent risk factors for SIRS induced by flexible ureteroscopic lithotripsy. Patients with these high-risk factors should be carefully evaluated to reduce systemic inflammatory response syndrome.
目的
探讨输尿管软镜钬激光碎石术引起全身炎症反应综合征（SIRS）的危险因素。方法：回顾性分析 2015 年 8 月至 2019 年 5 月连续 216 例行输尿管软镜钬激光碎石术的患者的临床资料。根据术后是否发生 SIRS 将患者分为 SIRS 组（21 例）和非 SIRS 组（195 例）。收集患者的年龄、性别、体质量指数、结石大小、手术时间、结石位置、肾盂积水、尿培养、住院时间、结石清除率、输尿管鞘、糖尿病等资料。采用单因素分析计算潜在的影响因素。为了确定各因素的独立性，对 SIRS 组和非 SIRS 组之间可能导致 SIRS 的因素进行比较。此外，采用多因素 logistic 回归分析确定输尿管软镜碎石术引起全身炎症反应综合征的危险因素。结果：所有患者均成功接受输尿管软镜碎石术治疗。输尿管软镜碎石术后 SIRS 的发生率为 9.7%。单因素分析显示，输尿管软镜碎石术引起 SIRS 的潜在危险因素为结石大小（ = 0.002）、手术时间（ = 0.002）、尿培养（ = 0.002）和输尿管鞘（ = 0.002）。多因素 logistic 回归分析显示，结石大小、手术时间、尿培养和输尿管鞘是输尿管软镜碎石术引起 SIRS 的独立危险因素。具有这些高危因素的患者应仔细评估，以减少全身炎症反应综合征的发生。
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