Fokom Domgue Joël, Chido-Amajuoyi Onyema G, Yu Robert K, Shete Sanjay
See the Notes section for the full list of authors' affiliations.
JNCI Cancer Spectr. 2019 Aug 27;3(4):pkz064. doi: 10.1093/jncics/pkz064. eCollection 2019 Dec.
Beliefs are known to be a key determinant in vaccines' uptake. However, little is known about beliefs surrounding the success of the human papillomavirus (HPV) vaccine in preventing cervical cancer in the United States.
Data from the Health Information National Trends Survey 5 Cycle 1 (2017) were analyzed for 1851 female respondents aged 18 years and older. Weighted multinomial logistic regression was employed to determine predictors of beliefs in the success of the HPV vaccine in preventing cervical cancer.
Overall, 29.8% of women believed that HPV vaccine is successful in preventing cervical cancer, 6.6% believed it is not successful, and 63.6% did not know if the HPV vaccine is successful. Non-Hispanic blacks (adjusted odds ratio [aOR] = 1.80, 95% confidence interval [CI] = 1.16 to 2.79), women with no more than 12 years of education (aOR = 2.05, 95% CI = 1.17 to 3.60), those who did not know if they were advised by a health-care provider to get an HPV shot within the last 12 months (aOR = 4.19, 95% CI = 1.39 to 12.60), and those unaware of a family cancer history (aOR = 5.17, 95% CI = 1.48 to 18.21) were more likely to not know whether the HPV vaccine prevents cervical cancer. Women younger than 65 years were more likely than elderly to believe that the HPV vaccine is not successful at preventing cervical cancer.
A substantial proportion of US women are uninformed about the HPV vaccine. To accelerate progress in the HPV vaccine's uptake, future interventions should incorporate educational programs, particularly targeting Non-Hispanic blacks, women with a lower level of education, and those younger than 65 years. Health-care providers' participation in promotion of patient education about HPV vaccination should also be increased.
众所周知，观念是影响疫苗接种率的关键因素。然而，在美国，人们对人乳头瘤病毒（HPV）疫苗预防宫颈癌成功率的相关观念却知之甚少。
对健康信息国家趋势调查第5轮第1周期（2017年）中1851名18岁及以上女性受访者的数据进行分析。采用加权多项逻辑回归来确定HPV疫苗预防宫颈癌成功率观念的预测因素。
总体而言，29.8%的女性认为HPV疫苗能成功预防宫颈癌，6.6%认为不能成功预防，63.6%不知道HPV疫苗是否能成功预防。非西班牙裔黑人（调整优势比[aOR]=1.80，95%置信区间[CI]=1.16至2.79）、受教育年限不超过12年的女性（aOR=2.05，95%CI=1.17至3.60）、在过去12个月内不知道是否有医疗保健人员建议其接种HPV疫苗的人（aOR=4.19，95%CI=1.39至12.60）以及不知道家族癌症病史的人（aOR=5.17，95%CI=1.48至18.21）更有可能不知道HPV疫苗能否预防宫颈癌。65岁以下的女性比老年人更有可能认为HPV疫苗不能成功预防宫颈癌。
相当一部分美国女性对HPV疫苗了解不足。为加快HPV疫苗的接种进程，未来的干预措施应纳入教育项目，尤其针对非西班牙裔黑人、教育程度较低的女性以及65岁以下的人群。还应增加医疗保健人员参与推广HPV疫苗接种患者教育的力度。
