Departments of Epidemiology and.
Contributed equally as co-first authors.
Pediatrics. 2021 Jun;147(6). doi: 10.1542/peds.2020-012765. Epub 2021 May 3.
Routine human papillomavirus (HPV) vaccination is recommended at ages 11 to 12 years and may be initiated as early as 9 years of age.
Data were derived from the National Immunization Survey-Teen, spanning 2008-2018. Using health care provider-verified vaccination histories, we examined trends in human papillomavirus vaccination up-to-date (HPV-UTD) rates within ages 9 to 12 years. Furthermore, we assessed vaccination status by sociodemographic factors and US state of residence.
Overall, amid evidence of recent stagnation, HPV vaccination between ages 9 to 12 increased over the years. Initiation rates rose from 17.3% in 2008 to 62.8% in 2018, and HPV-UTD rates rose from 13.5% in 2011 to 32.8% in 2018. After the inception of gender-neutral HPV vaccination, HPV-UTD rates between 2011 and 2018 rose by 31.9% among boys and only 6.6% among girls. For most of the study period, non-Hispanic Black and Hispanic individuals had higher rates of initiation and HPV-UTD than non-Hispanic white individuals. In 2018, vaccination initiation rates exceeded 70% in several states; however, HPV-UTD rates in most US states were <50%, excluding Rhode Island (61.6%), Colorado (58.7%), Hawaii (53.5%), District of Columbia (53.2%), and Ohio (50%).
HPV vaccination within ages 9 to 12 years is suboptimal. To leverage the substantial benefits of HPV vaccination within this age range, it is imperative that conscious efforts are taken at the national and state levels to promote HPV vaccination for this age group.
建议在 11 至 12 岁时进行常规人乳头瘤病毒(HPV)疫苗接种,并且可以在 9 岁时开始接种。
数据来自 2008 年至 2018 年的国家免疫调查-青少年。使用医疗保健提供者验证的疫苗接种记录,我们检查了 9 至 12 岁之间人乳头瘤病毒疫苗接种的最新(HPV-UTD)率趋势。此外,我们还根据社会人口统计学因素和美国居住州评估了疫苗接种状况。
总体而言,尽管最近出现了停滞,但在 9 至 12 岁之间进行 HPV 疫苗接种的人数有所增加。启动率从 2008 年的 17.3%上升到 2018 年的 62.8%,HPV-UTD 率从 2011 年的 13.5%上升到 2018 年的 32.8%。在实施性别中性 HPV 疫苗接种之后,2011 年至 2018 年之间男孩的 HPV-UTD 率上升了 31.9%,而女孩的 HPV-UTD 率仅上升了 6.6%。在研究期间的大部分时间里,非西班牙裔黑人和西班牙裔人群的启动率和 HPV-UTD 率均高于非西班牙裔白人。在 2018 年,几个州的疫苗接种启动率超过了 70%;但是,大多数美国州的 HPV-UTD 率<50%,除了罗得岛州(61.6%),科罗拉多州(58.7%),夏威夷州(53.5%),哥伦比亚特区(53.2%)和俄亥俄州(50%)。
9 至 12 岁之间的 HPV 疫苗接种效果不佳。为了在该年龄段内充分利用 HPV 疫苗接种的巨大益处,国家和州一级必须做出积极努力,促进该年龄段的 HPV 疫苗接种。