Departments of Obstetrics and Gynecology, Pathology, and Radiology, University of Utah Health, Intermountain Healthcare, and Primary Children's Hospital, Salt Lake City, Utah.
Obstet Gynecol. 2020 May;135(5):1104-1111. doi: 10.1097/AOG.0000000000003793.
For decades, placenta accreta spectrum disorder has been classified, staged, and described as a disorder of placental invasion. In this commentary, we argue that placenta accreta spectrum exists as a disorder of defective decidua and uterine scar dehiscence, not as a disorder of destructive trophoblast invasion. Adopting this understanding of placenta accreta spectrum will help direct research efforts and clinical resources toward the prevention, accurate diagnosis, and safe treatment of this devastating-and increasingly common-disorder.
几十年来,胎盘植入谱系疾病一直被归类、分期和描述为胎盘入侵的疾病。在本评论中,我们认为胎盘植入谱系的存在是蜕膜缺陷和子宫瘢痕裂开的疾病,而不是破坏性滋养细胞侵袭的疾病。采用这种对胎盘植入谱系的理解将有助于指导研究工作和临床资源,以预防、准确诊断和安全治疗这种破坏性的疾病。