Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira I Virgili, Sant Llorens 21, 43201, Reus, Catalonia, Spain.
Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira I Virgili, Sant Llorens 21, 43201, Reus, Catalonia, Spain.
Environ Res. 2020 Jul;186:109495. doi: 10.1016/j.envres.2020.109495. Epub 2020 Apr 8.
Petrochemical complexes and oil refineries are well known sources of a wide range of environmental pollutants. Consequently, the potential harmful health effects of living near these facilities is a topic of concern among the population living in the neighborhood. Anyhow, the number of studies carried out on this issue is rather limited and, in some cases, results are even slightly contradictory. The present Review was aimed at assessing whether living in the vicinity of petrochemical industries and oil refineries is associated with a higher incidence of cancer and cancer mortality. In this sense, up to 23 investigations were found in PubMed and Scopus databases. According to the type of cancer, leukemia and other hematological malignancies were reported as the main types of cancer for populations living in the neighborhood of petrochemical industries. This was concluded based on studies performed in Taiwan, Spain, United Kingdom, Italy and Nigeria. In contrast, no association was found in 4 different investigations conducted in Sweden, Finland and USA with the same purpose. Other scientific studies reported a high incidence of lung and bladder cancer in Taiwan, Italy and USA, as well as an excess mortality of bone, brain, liver, pleural, larynx and pancreas cancers in individuals living near petrochemical complexes from Taiwan, Spain, Italy, United Kingdom and USA. Thus, human exposure to certain carcinogenic pollutants emitted from petrochemical industries might increase the incidence of some cancers and cancer mortality. Anyway, since the limited number of investigations conducted until now, further studies are required in order to corroborate -in a more generalized way-this conclusion.
石化综合体和炼油厂是众所周知的各种环境污染物的来源。因此，居住在这些设施附近对健康可能产生的有害影响是居住在附近的人们关注的话题。尽管如此，关于这个问题的研究数量相当有限，而且在某些情况下，结果甚至略有矛盾。本综述旨在评估居住在石化工业和炼油厂附近是否与癌症发病率和癌症死亡率升高有关。为此，在 PubMed 和 Scopus 数据库中找到了多达 23 项研究。根据癌症类型，居住在石化工业附近的人群报告的主要癌症类型为白血病和其他血液恶性肿瘤。这是基于在台湾、西班牙、英国、意大利和尼日利亚进行的研究得出的结论。相比之下，在瑞典、芬兰和美国进行的四项具有相同目的的不同研究中，没有发现相关性。其他科学研究报告在台湾、意大利和美国，肺癌和膀胱癌的发病率较高，以及居住在来自台湾、西班牙、意大利、英国和美国的石化综合体附近的个体中骨癌、脑癌、肝癌、胸膜癌、喉癌和胰腺癌的死亡率过高。因此，人类接触石化工业排放的某些致癌污染物可能会增加某些癌症的发病率和癌症死亡率。无论如何，由于迄今为止进行的研究数量有限，需要进一步研究以更普遍的方式证实这一结论。
