夜班工作者出现更高的尿路症状，并伴有生活质量受损：一项单队列研究。

Night shift workers refer higher urinary symptoms with an impairment quality of life: a single cohort study.

机构信息

Department of Urology, Sant'Andrea Hospital, Sapienza University, Rome, Italy -

Department of Urology, Sant'Andrea Hospital, Sapienza University, Rome, Italy.

出版信息

Minerva Urol Nephrol. 2021 Dec;73(6):831-835. doi: 10.23736/S2724-6051.20.03735-2. Epub 2020 Apr 10.

DOI:10.23736/S2724-6051.20.03735-2

PMID:32284530

Abstract

BACKGROUND

The aim of the present study is to assess the impact of night shift work (NSW) on urinary symptoms.

METHODS

Between March 2018 to October 2018, we evaluated a group of National Health care system workers. Urinary symptoms and quality of life were measured by Overactive Bladder Questionnaire Short Form (OABq-sf). Clinical variables (i.e. age, smoking status, medical history) were collected and analyzed according to be NS workers (NSWs) from subjects working at least one time from 8 pm to 8 am or from traditional workers (TWs). Univariate and multivariate analysis was performed to identify predictive variables of worse OAB outcomes (OABq-sf>30, OABq-SB≥12, OABq HRQL≥18).

RESULTS

A total of 136 participants (68 males and 68 females) were included in the study. On OABq-sf, total score, symptoms bother (OABq-SB) and health related quality of life (OABq-HRQL) domains were significantly (P<0.05) higher in NSWs group, respectively: 31 (IQR 26-35) vs. 19 (IQR 19-20); 11 (IQR 10-13) vs. 6 (IQR 6-7); 19 (IQR 16-22) vs. 13 (13-14). Finally, seven NSWs (10.6%) referred nocturia respect to only one (1%) TWs, (P=0.02). On multivariate analysis NSW was an independent predictor of OABq-sf>30 units (OR:30; CI: 9-111, P=0.001), OABq-SB ≥12 units (OR:16, CI: 6-43, P=0.001) and OABq HRQL≥18 units (OR:20, CI: 6-70, P=0.001).

CONCLUSIONS

Night shift workers presented worst OAB Score and poor QL when compared to similar traditional workers. Long-term data on NSWs patients are also needed to further clarify this relationship.

摘要

背景

本研究旨在评估夜班工作（NSW）对泌尿系统症状的影响。

方法

2018 年 3 月至 10 月期间，我们评估了一组国家医疗保健系统的工作人员。通过膀胱过度活动症问卷短表（OABq-sf）评估泌尿系统症状和生活质量。根据工作人员是否为上夜班者（NSWs），即至少有一次工作时间为晚上 8 点至早上 8 点，或为传统工作者（TWs），收集并分析临床变量（即年龄、吸烟状况、病史）。采用单变量和多变量分析来确定更差的 OAB 结局（OABq-sf>30、OABq-SB≥12、OABq-HRQL≥18）的预测变量。

结果

共有 136 名参与者（68 名男性和 68 名女性）纳入本研究。在 OABq-sf 上，总评分、症状困扰（OABq-SB）和健康相关生活质量（OABq-HRQL）领域在 NSWs 组中显著更高（P<0.05）：31（IQR 26-35）vs. 19（IQR 19-20）；11（IQR 10-13）vs. 6（IQR 6-7）；19（IQR 16-22）vs. 13（13-14）。最后，7 名 NSWs（10.6%）出现夜间多尿，而仅 1 名 TWs（1%）出现（P=0.02）。多变量分析表明，NSW 是 OABq-sf>30 单位的独立预测因子（OR：30；95%CI：9-111，P=0.001）、OABq-SB≥12 单位的独立预测因子（OR：16；95%CI：6-43，P=0.001）和 OABq HRQL≥18 单位的独立预测因子（OR：20；95%CI：6-70，P=0.001）。