Mamaeva Tatiana, Mehlum Camilla Slot, Davidsen Jesper Rømhild
Department of Respiratory Medicine, Odense University Hospital, Denmark.
Department of ORL-Head and Neck Surgery, Odense University Hospital, Odense, Denmark.
Eur Clin Respir J. 2020 Mar 12;7(1):1740567. doi: 10.1080/20018525.2020.1740567. eCollection 2020.
Radiological presentation of bronchiectasis should prompt the respiratory physician to investigate various differential diagnosis leading to this condition. This case report describes a young non-smoking woman with HPV11 induced laryngeal Recurrent Respiratory Papillomatosis (RRP) since early childhood, who developed progressive exertional dyspnea. A thorough diagnostic process revealed HPV11 infection in the lung parenchyma consistent with RRP in the lower airways, an HPV infection that was most likely obtained from the patient´s mother during vaginal birth. This case report illustrates that also respiratory physicians should keep RRP in mind in persons with the radiological presentation of bronchiectasis previously diagnosed RRP in the upper airways.
支气管扩张的影像学表现应促使呼吸内科医生对导致这种情况的各种鉴别诊断进行调查。本病例报告描述了一名自幼患有HPV11诱导的喉复发性呼吸道乳头状瘤病（RRP）的年轻不吸烟女性，她出现了进行性运动性呼吸困难。全面的诊断过程显示肺实质中存在HPV11感染，与下呼吸道的RRP一致，这种HPV感染很可能是患者在阴道分娩时从其母亲那里获得的。本病例报告表明，对于先前被诊断为上呼吸道RRP且有支气管扩张影像学表现的患者，呼吸内科医生也应考虑到RRP。
