Department of Oral Pathology and Oral Biology, School of Dentistry, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Department of Anatomical Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Head Neck Pathol. 2021 Mar;15(1):298-302. doi: 10.1007/s12105-020-01160-0. Epub 2020 Apr 13.
Sublingual dermoid cysts and oral heterotopic gastrointestinal cysts are well-documented causes of sublingual swellings in infants. However, the simultaneous occurrence of both cysts is an extremely rare phenomenon, with only two previous cases reported in literature. We present a case of 1-month-old neonate with a cystic ventral tongue mass that on histologic examination showed a dermoid cyst with co-existing heterotopic gastric-type epithelium in the wall. Additional histochemical stains revealed focal areas of colonic metaplasia within the heterotopic gastric epithelium. CDX2 immunohistochemical staining confirmed derivation from colonic epithelium.
舌下皮样囊肿和口腔异位胃肠囊肿是婴儿舌下肿胀的已知病因。然而,这两种囊肿同时发生是一种极其罕见的现象,文献中仅报道过两例。我们报告了一例 1 个月大的新生儿,其囊性舌腹肿块在组织学检查中显示为皮样囊肿,囊壁内同时存在异位胃型上皮。额外的组织化学染色显示异位胃上皮内存在结肠化生的局灶区域。CDX2 免疫组织化学染色证实来源于结肠上皮。