经皮胆红素测定法。光照对皮肤胆红素指数的影响。

Transcutaneous bilirubinometry. Effect of irradiation on the skin bilirubin index.

作者信息

Yamauchi Y, Yamanouchi I

机构信息

Department of Pediatrics, Children's Medical Center, Okayama National Hospital, Japan.

出版信息

Biol Neonate. 1988;54(6):314-9. doi: 10.1159/000242870.

DOI:10.1159/000242870

PMID:3228560

Abstract

We studied the relation between irradiation and the percent decrease of skin and serum bilirubin during phototherapy. There was a significant positive correlation between the percent decrease of transcutaneous bilirubinometry readings at the sites exposed directly to light (chest) and irradiation (r = 0.593, p less than 0.001, n = 32). A significant positive correlation was also found between the percent decrease of serum bilirubin concentration and irradiation (r = 0.587, p less than 0.001, n = 32), and the percent decrease of skin bilirubin at exposed sites (chest) and the percent decrease of serum bilirubin concentration (r = 0.481, p less than 0.001, n = 32). Thus, light energy quantitatively affects skin and serum bilirubin. In order to determine the optimal effective wavelength and irradiation energy for phototherapy, it is necessary to examine skin bilirubin kinetics in detail during phototherapy.

摘要

我们研究了光疗期间照射与皮肤及血清胆红素降低百分比之间的关系。直接暴露于光的部位（胸部）经皮胆红素测定读数的降低百分比与照射之间存在显著正相关（r = 0.593，p < 0.001，n = 32）。血清胆红素浓度的降低百分比与照射之间也发现显著正相关（r = 0.587，p < 0.001，n = 32），以及暴露部位（胸部）皮肤胆红素的降低百分比与血清胆红素浓度的降低百分比之间（r = 0.481，p < 0.001，n = 32）。因此，光能在数量上影响皮肤和血清胆红素。为了确定光疗的最佳有效波长和照射能量，有必要在光疗期间详细检查皮肤胆红素动力学。