尼多病毒目病毒的基因组组织：动脉炎病毒、圆环病毒和冠状病毒之间的异同
The Genome Organization of the Nidovirales: Similarities and Differences between Arteri-, Toro-, and Coronaviruses.
作者信息
de Vries Antoine A F, Horzinek Marian C, Rottier Peter J M, de Groot Raoul J
机构信息
Virology Unit, Department of Infectious Diseases and Immunology, Veterinary Faculty, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, The Netherlands.
出版信息
Semin Virol. 1997 Feb;8(1):33-47. doi: 10.1006/smvy.1997.0104. Epub 2002 May 25.
Abstract
Viruses in the families Arteriviridae and Coronaviridae have enveloped virions which contain nonsegmented, positive-stranded RNA, but the constituent genera differ markedly in genetic complexity and virion structure. Nevertheless, there are striking resemblances among the viruses in the organization and expression of their genomes, and sequence conservation among the polymerase polyproteins strongly suggests that they have a common ancestry. On this basis, the International Committee on Taxonomy of Viruses recently established a new order, Nidovirales, to contain the two families. Here, the common traits and distinguishing features of the Nidovirales are reviewed.
摘要
动脉炎病毒科和冠状病毒科的病毒具有包膜病毒粒子，其包含不分节段的正链RNA，但各组成属在遗传复杂性和病毒粒子结构上有显著差异。然而，这些病毒在基因组的组织和表达方面存在显著相似性，聚合酶多聚蛋白之间的序列保守性强烈表明它们有共同的祖先。基于此，国际病毒分类委员会最近设立了一个新的目——网巢病毒目，包含这两个科。在此，对网巢病毒目的共同特征和区别特征进行综述。
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