重新思考放射治疗在上皮性卵巢癌管理中的作用。
Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer.
作者信息
Jacobson Geraldine, Galvan-Turner Valerie
机构信息
Department of Radiation Oncology, West Virginia University, Morgantown WV 26505-9234, USA.
Department of Obstetrics and Gynecology, West Virginia University, Morgantown WV 26505-9234, USA.
出版信息
Diagnostics (Basel). 2020 Apr 11;10(4):211. doi: 10.3390/diagnostics10040211.
Radiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image-guided radiation therapy, enable conformal treatment that controls local disease with minimal morbidity. Recent studies from multiple institutions support the role of radiation in the ablative treatment of oligometastatic disease and control of locally recurrent and metastatic disease. Effective local treatment with radiation complements the role of systemic therapy in the management of EOC; reduces symptoms and disease burden, and may contribute to a prolonged drug free interval.
在上皮性卵巢癌（EOC）的治疗中，放射治疗已沦为一种姑息性手段。包括调强放射治疗（IMRT）、立体定向体部放射治疗（SBRT）以及图像引导放射治疗在内的当代放射技术，能够实现适形治疗，以最低的发病率控制局部疾病。来自多个机构的近期研究支持放射治疗在寡转移疾病的消融治疗以及局部复发和转移疾病控制中的作用。放射治疗进行有效的局部治疗，可补充全身治疗在EOC治疗中的作用；减轻症状和疾病负担，并可能有助于延长无药间期。
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