对选定药用植物中酚类和黄酮类成分的自由基清除及细胞毒性活性的比较分析。
Comparative analyses on radical scavenging and cytotoxic activity of phenolic and flavonoid content from selected medicinal plants.
作者信息
Ng Zhi Xiang, Koick Yvonne Tyng Tying, Yong Phaik Har
机构信息
School of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Selangor, Malaysia.
School of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Selangor, Malaysia.
出版信息
Nat Prod Res. 2021 Dec;35(23):5271-5276. doi: 10.1080/14786419.2020.1749617. Epub 2020 Apr 14.
This study aimed to compare the total phenolic (TPC), flavonoid (TFC), radical scavenging and cytotoxic activities in the aqueous methanolic extracts of , , , and with two dietary plants: and . The TPC and TFC in medicinal plant extracts were 12-93% lower than as follows: > > . > > The decreasing radical scavenging activity in medicinal plant extracts shared similar trend: > > . > > Both TPC and TFC were positively correlated with radical scavenging and cytotoxic activities. All medicinal plants were considered inactive (LC > 0.2 mg/ml) and safe for consumption. The TPC, TFC, radical scavenging and cytotoxic activities in the medicinal plants were plant-part dependant, in particular and .
本研究旨在比较[具体植物名称1]、[具体植物名称2]、[具体植物名称3]、[具体植物名称4]和[具体植物名称5]的甲醇水提取物与两种食用植物[具体食用植物名称1]和[具体食用植物名称2]中的总酚（TPC）、黄酮（TFC）、自由基清除和细胞毒性活性。药用植物提取物中的TPC和TFC比[具体对比对象]低12 - 93%，如下所示：[具体植物名称1]>[具体植物名称2]>[具体植物名称3]。[具体植物名称4]>[具体植物名称5]>[具体植物名称3] 药用植物提取物中自由基清除活性的降低呈现相似趋势：[具体植物名称1]>[具体植物名称2]>[具体植物名称3]。[具体植物名称4]>[具体植物名称5]>[具体植物名称3] TPC和TFC均与自由基清除和细胞毒性活性呈正相关。所有药用植物均被认为无活性（LC>0.2毫克/毫升）且食用安全。药用植物中的TPC、TFC、自由基清除和细胞毒性活性取决于植物部位，特别是[具体植物部位1]和[具体植物部位2]。
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