Technical University of Berlin, Straße des 17. Juni 124, 10623, Berlin, Germany.
Technical University of Berlin, Straße des 17. Juni 124, 10623, Berlin, Germany.
Biosens Bioelectron. 2020 Jul 1;159:112165. doi: 10.1016/j.bios.2020.112165. Epub 2020 Mar 26.
The last decade has witnessed an immense demand for the development of new glucose biosensors. The research has mainly focused on achieving biocompatible and improved sensing capabilities as compared to the current technologies, which opens new directions toward more efficient glucose sensors. These sensing platforms have been continuously evolving with the contribution of novel materials, such as gold, platinum, metal alloys/adatom, graphene, composites and glucose-specific organic materials, owing to their electrocatalytic response to the oxidation of glucose. The chief motive of this review is to cover the recent advances on enzymatic and non-enzymatic glucose sensors evolved in the last four years. We discuss the sensor fabrication methods, the materials and nanostructures involved, the detection principles and the performance of the sensors in whole blood, saliva, urine or interstitial fluids in detail.
过去十年见证了人们对开发新型葡萄糖生物传感器的巨大需求。研究主要集中在实现生物相容性和提高传感性能方面，与当前技术相比，这为更高效的葡萄糖传感器开辟了新的方向。这些传感平台通过新型材料（如金、铂、金属合金/原子、石墨烯、复合材料和葡萄糖特异性有机材料）的贡献不断发展，因为它们对葡萄糖氧化具有电催化响应。本综述的主要目的是涵盖过去四年中酶和非酶葡萄糖传感器的最新进展。我们详细讨论了传感器的制造方法、所涉及的材料和纳米结构、检测原理以及在全血、唾液、尿液或间质液中的传感器性能。
