Aygun Aysenur, Ozveren Esra, Halvaci Ebru, Ikballi Damla, Elhouda Tiri Rima Nour, Catal Cansu, Bekmezci Muhammed, Ozengul Alper, Kaynak Idris, Sen Fatih
Sen Research Group, Biochemistry Department, Faculty of Arts and Science, Kutahya Dumlupinar University Evliya Celebi Campus 43100 Kutahya Turkiye
Department of Materials Science & Engineering, Faculty of Engineering, Dumlupinar University Evliya Celebi Campus 43100 Kutahya Turkiye.
RSC Adv. 2024 Nov 1;14(47):34964-34970. doi: 10.1039/d4ra06566b. eCollection 2024 Oct 29.
Fluorescent glucose sensors often utilize nanotechnology to detect glucose in a sensitive and targeted manner. Nanoscale materials increase the sensitivity and efficiency of sensors by better understanding and managing the properties and interactions of the structure to be sensed. Nitrogen-doped carbon quantum dots (N-CQD), which work with the concept of fluorescence quenching or switching on because of specific processes in the presence of glucose, are one type of nanoscale material added to these sensors. In the field of biological material identification, this state-of-the-art technology is recognized as a useful tool. In this work, copper nanostructure-supported nitrogen-doped carbon quantum dots (Cu@N-CQDs) were synthesized by the hydrothermal method. The shape and structure of the fabricated materials were characterized using fluorescence (FL) spectrophotometry, Fourier Transform Infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), X-ray diffraction, and UV-visible spectrophotometry (UV-vis). The proposed sensor has a linear range of 0-140 μM and a limit of detection (LOD) of 29.85 μM, showing high sensitivity and selectivity for glucose sensing by FL. The developed sensor was successfully applied to detect glucose and demonstrated the potential of Cu@N-CQDs as promising candidates for designing sensors for glucose measurement.
荧光葡萄糖传感器通常利用纳米技术以灵敏且有针对性的方式检测葡萄糖。纳米级材料通过更好地理解和掌控待检测结构的特性及相互作用,提高了传感器的灵敏度和效率。氮掺杂碳量子点(N-CQD)因在葡萄糖存在时的特定过程会产生荧光猝灭或开启现象,是添加到这些传感器中的一种纳米级材料。在生物材料识别领域,这项先进技术被视为一种有用的工具。在本研究中,采用水热法合成了铜纳米结构负载的氮掺杂碳量子点(Cu@N-CQDs)。使用荧光(FL)分光光度法、傅里叶变换红外光谱(FT-IR)、透射电子显微镜(TEM)、X射线衍射和紫外可见分光光度法(UV-vis)对所制备材料的形状和结构进行了表征。所提出的传感器线性范围为0 - 140 μM,检测限(LOD)为29.85 μM,通过荧光对葡萄糖传感表现出高灵敏度和选择性。所开发的传感器成功应用于检测葡萄糖,并证明了Cu@N-CQDs作为设计葡萄糖测量传感器的有潜力的候选材料的可能性。