Brozena S J, Cohen L E, Fenske N A
Dermatology Division, University of South Florida College of Medicine, Tampa.
Cutis. 1988 Dec;42(6):512-5.
Folliculitis decalvans is a rare follicular inflammatory disease of the scalp. It is characterized by initial perifollicular inflammatory changes followed by peripheral extension and eventual circumscribed patches of cicatricial alopecia. The disease is known for its resistance to treatment, resulting in an unfavorable prognosis. The cause of the disease is unknown, although a bacterial etiology is postulated. We report a classic case that was temporized with various antibiotics and only subsequently resolved after ten weeks of therapy with rifampin. The patient has remained free of disease for more than one year. We present a brief review of the cicatricial alopecias and discuss rifampin therapy for this condition.
脱发性毛囊炎是一种罕见的头皮毛囊炎性疾病。其特征为起初的毛囊周围炎性改变,随后向周围扩展,最终形成局限性瘢痕性脱发斑。该疾病因治疗抵抗而闻名,导致预后不佳。尽管推测有细菌病因,但疾病的原因尚不清楚。我们报告一例典型病例,先用多种抗生素进行了临时治疗,仅在使用利福平治疗十周后才得以痊愈。该患者已一年多未再发病。我们简要综述瘢痕性脱发,并讨论利福平对这种疾病的治疗。