Razvan Creteanu, Popa Monica, Incze Ana-Maria, Cristina Creteanu
Dr. Creteanu Razvan, UMF. Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Dr. Monica Popa, UMF. Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Pak J Med Sci. 2020 Mar-Apr;36(3):349-354. doi: 10.12669/pjms.36.3.1820.
This study estimated the concentration of Ca, Mg and F in drinking water from five counties in Transylvania, Romania and correlated these with mineral values found in the dentine of permanent carious teeth. The role of these minerals on the re-mineralization of teeth is broadly analyzed.
The study consists of two parts: the first part is a pilot study aimed at determining the concentration of Ca, Mg and F in the dentine of permanent carious teeth of 75 male adults with residence in five counties in Transylvania. The second part is an evaluation of the levels of mineral composition in the drinking water from these counties. Mineral concentrations in dentine and drinking water samples, were determined in the laboratories of the public health institute and the research and analysis institute in Cluj Napoca, Romania.
Statistically we found a direct and significant correlation between the Ca, Mg and F contain from the water samples and Ca, Mg and F contain from the dentine samples and an inverse correlation was statistically highlighted between Ca found in water samples and the F concentration in dentine samples. Improperly water mineralization associated with a general lack of fluoride reveals a potential negative impact on consumer health, including the oral-jaw system.
The results of this study indicate the need for improving the prevention of dental caries which is a priority in promoting orthodontic health for children. The variability in dentine minerals indicates the fact that permanent molar dentin represents an important biomarker for exposure. The future research will have to take into consideration the community residency status and the fact that these studies require a large sample to separate individual and community level contributions to dentin fluoride. Considering these notifications, we conclude that minerals are highly associated with caries.
本研究估算了罗马尼亚特兰西瓦尼亚五个县饮用水中钙、镁和氟的浓度，并将这些浓度与恒牙龋牙牙本质中的矿物质含量进行关联。对这些矿物质在牙齿再矿化中的作用进行了广泛分析。
该研究包括两个部分：第一部分是一项初步研究，旨在确定居住在特兰西瓦尼亚五个县的75名成年男性恒牙龋牙牙本质中钙、镁和氟的浓度。第二部分是对这些县饮用水中矿物质成分水平的评估。牙本质和饮用水样本中的矿物质浓度在罗马尼亚克卢日 - 纳波卡的公共卫生研究所和研究分析研究所的实验室中测定。
从统计学角度，我们发现水样中的钙、镁和氟含量与牙本质样本中的钙、镁和氟含量之间存在直接且显著的相关性，并且统计学上突出显示水样中钙与牙本质样本中氟浓度之间呈负相关。与普遍缺乏氟相关的水矿化不当揭示了对消费者健康，包括口腔颌面部系统的潜在负面影响。
本研究结果表明需要加强龋齿预防，这是促进儿童口腔正畸健康的优先事项。牙本质矿物质的变异性表明恒牙磨牙牙本质是暴露的重要生物标志物这一事实。未来的研究将不得不考虑社区居住状况以及这些研究需要大样本以区分个体和社区层面因素对牙本质氟含量的影响这一事实。考虑到这些情况，我们得出结论，矿物质与龋齿高度相关。
