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一名儿科患者患有多发颅内结核瘤及脊髓髓内结核瘤

Multiple Intracranial Tuberculomas with an Intra-medullary Spinal Cord Tuberculoma in a Pediatric Patient.

作者信息

Meegada Sreenath, Gyamfi Richmond, Muppidi Vijayadershan, Dandu Vasuki, Challa Tejo

机构信息

Internal Medicine, The University of Texas Health Science Center/Christus Good Shepherd Medical Center, Longview, USA.

Internal Medicine, Prevea Health, De Pere, USA.

出版信息

Cureus. 2020 Mar 12;12(3):e7248. doi: 10.7759/cureus.7248.

Abstract

Central nervous system (CNS) tuberculosis (TB), caused by Mycobacterium tuberculosis (MT), is a severe form of TB, which presents as meningitis, cerebritis, abscesses, spinal tuberculous arachnoiditis, and rarely tuberculomas. CNS TB is prevalent in the underdeveloped or developing world and is common in malnourished, alcoholics, children, young adults, immunocompromised, and cancer patients. Intracranial tuberculomas (ICT) can present with symptoms and signs of focal neurological deficits with or without systemic manifestations. ICT is the least common presentation of CNS TB. Medical management with anti-TB drugs and steroids is the mainstay of treatment, while surgical intervention is usually reserved for refractory cases. Here, we present the case of a 10-year-old Indian American girl with headaches, diplopia, fever, and neck pain diagnosed with ICT and intramedullary spinal cord tuberculoma.

摘要

中枢神经系统(CNS)结核(TB)由结核分枝杆菌(MT)引起,是一种严重的结核病形式,表现为脑膜炎、脑炎、脓肿、脊柱结核性蛛网膜炎,很少见结核瘤。中枢神经系统结核在不发达或发展中世界流行,在营养不良者、酗酒者、儿童、年轻人、免疫功能低下者和癌症患者中很常见。颅内结核瘤(ICT)可伴有或不伴有全身表现,出现局灶性神经功能缺损的症状和体征。颅内结核瘤是中枢神经系统结核最不常见的表现形式。使用抗结核药物和类固醇进行药物治疗是主要的治疗方法,而手术干预通常仅用于难治性病例。在此,我们报告一例10岁的印度裔美国女孩,她因头痛、复视、发热和颈部疼痛被诊断为颅内结核瘤和脊髓内结核瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f77c/7152571/dfeaa654cfb5/cureus-0012-00000007248-i01.jpg

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