Yang Yong, Jiao Yanqin, Yu Jieqing, Wang Chenxiu
Department of Vascular Mammary Surgery (Thyroid and Hernia), Jiangxi Provincial People's Hospital, Nanchang University, Nanchang, 330006, P.R. China.
Department of Nursing, Jiangxi Health Vocational College, Nanchang, 330052, P.R. China.
Iran J Public Health. 2019 Aug;48(8):1461-1468.
To investigate the treatment efficacy of radioactive iodine therapy on patients after total thyroidectomy and its effect on the quality of life.
A retrospective analysis of clinical data of 120 thyroid cancer patients admitted to Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China from February 2014 to February 2017 was performed. According to different treatment methods, they were divided into observation group of 62 cases and control group of 58 cases. Both groups were treated with total thyroidectomy. The control group was treated with anti-infection and prevention of complications after operation, the observation group with radioactive iodine therapy. Treatment efficacy, quality of life score, recurrent laryngeal nerve injury and postoperative survival rate were compared between the two groups.
The total effective rate of treatment in the test group was 98.39%, significantly higher than 72.41% in the control group, with a statistically significant difference (<0.05). Compared with the control group, the fatigue score of the test group was lower, but the score in the area of emotion function and the overall health status score were higher, with a statistically significant difference (<0.05). There was no significant difference in the recurrent laryngeal nerve injury between the two groups of patients. The postoperative survival rate of the test group of patients was 96.77%, significantly higher than 86.21% of the control group.
The effect of radioactive iodine therapy after total thyroidectomy is remarkable, which can significantly improve the clinical treatment efficacy and postoperative quality of life of patients, worthy of clinical application.
探讨放射性碘治疗对全甲状腺切除术后患者的治疗效果及其对生活质量的影响。
对2014年2月至2017年2月在中国南昌大学附属江西省人民医院收治的120例甲状腺癌患者的临床资料进行回顾性分析。根据不同治疗方法，将其分为观察组62例和对照组58例。两组均行全甲状腺切除术。对照组术后给予抗感染及预防并发症治疗，观察组给予放射性碘治疗。比较两组的治疗效果、生活质量评分、喉返神经损伤情况及术后生存率。
试验组治疗总有效率为98.39%，显著高于对照组的72.41%，差异有统计学意义（<0.05）。与对照组相比，试验组疲劳评分较低，但情绪功能领域评分及总体健康状况评分较高，差异有统计学意义（<0.05）。两组患者喉返神经损伤情况差异无统计学意义。试验组患者术后生存率为96.77%，显著高于对照组的86.21%。
全甲状腺切除术后放射性碘治疗效果显著，可显著提高患者的临床治疗效果及术后生活质量，值得临床应用。
