Fischer Thomas H
Dtsch Med Wochenschr. 2020 Apr;145(8):526-535. doi: 10.1055/a-0969-6402. Epub 2020 Apr 15.
The use of medical antiarrhythmic therapy apart from beta-blockers has been steadily decreasing in the recent past. This can partly be attributed to technological progress that has rendered the ablation of complex cardiac arrhythmias like atrial fibrillation, focal atrial tachycardias and ventricular arrhythmias feasible and efficacious. Furthermore, an awareness regarding pro-arrhythmic and toxic side-effects of antiarrhythmic medication has evolved. Nevertheless, medical antiarrhythmic therapy still plays a fundamental role in acute therapy of arrythmias as well as certain indications for long-term therapy. This review comprehensively summarizes the current role of medical antiarrhythmic therapy in daily clinical practice focusing on mechanisms and therapies of the most common cardiac arrythmias.
除β受体阻滞剂外,医学抗心律失常治疗的使用在最近一直在稳步下降。这部分可归因于技术进步,使得诸如心房颤动、局灶性房性心动过速和室性心律失常等复杂心律失常的消融变得可行且有效。此外,人们对抗心律失常药物的促心律失常和毒性副作用的认识也有所提高。尽管如此,医学抗心律失常治疗在心律失常的急性治疗以及某些长期治疗适应症中仍发挥着重要作用。本综述全面总结了医学抗心律失常治疗在日常临床实践中的当前作用,重点关注最常见心律失常的机制和治疗方法。