Zhang H X, Han M J, Zhou Y, Xiu X F, Xu F, Wang L
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Mar 10;41(3):406-411. doi: 10.3760/cma.j.issn.0254-6450.2020.03.024.
To analyze influence on HIV related fatality of implementation of 'Four Free Services One Care' policy in China during 1993-2012, and evaluate effectiveness for the policy of HIV/AIDS prevention and treatment. The data during 1993-2003 (before the implementation of the policy) and during 2005-2012 (after the implementation of the policy) were collected from the national HIV/AIDS Comprehensive Response Information Management System for the analysis on HIV related fatality in Chinese, especially in rural residents. Interrupted time series analysis was used to analyze the trends of HIV related fatality during 1993 and 2012. During the twenty years from 1993 to 2012, the HIV related fatality in China decreased, and the HIV related fatality in rural areas was higher than the overall HIV related fatality. Compared with the period before the implementation of the policy, the overall HIV related fatality decreased by 1.5 (=0.156) and the HIV related fatality in rural residents decreased by 2.6 in 2004 when the policy was implemented (=0.094). As for the change of slope, the overall slope rate after the policy implementation was -0.466 (=0.005), indicating a decrease trend of HIV related fatality. The slope rate after the policy implementation in rural residents was-0.592 (=0.005), indicating a decrease trend of HIV related fatality. At the same time, the slope rate after the policy implementation in rural residents infected through blood transmission route was-0.766 (<0.001), indicating a decrease trend of HIV related fatality. The implementation of the 'Four Free Services One Care' policy in China has made remarkable progress in free HIV antiviral therapy.
分析1993 - 2012年中国实施“四免一关怀”政策对艾滋病相关死亡的影响，并评估该政策在艾滋病防治方面的效果。收集1993 - 2003年（政策实施前）和2005 - 2012年（政策实施后）的数据，来自国家艾滋病综合防治信息管理系统，用于分析中国尤其是农村居民的艾滋病相关死亡情况。采用中断时间序列分析方法分析1993年至2012年艾滋病相关死亡的趋势。1993年至2012年的二十年里，中国艾滋病相关死亡人数下降，农村地区的艾滋病相关死亡率高于总体艾滋病相关死亡率。与政策实施前相比，2004年政策实施时总体艾滋病相关死亡率下降了1.5（=0.156），农村居民艾滋病相关死亡率下降了2.6（=0.094）。关于斜率变化，政策实施后的总体斜率率为 - 0.466（=0.005），表明艾滋病相关死亡率呈下降趋势。农村居民政策实施后的斜率率为 - 0.592（=0.005），表明艾滋病相关死亡率呈下降趋势。同时，经血液传播途径感染的农村居民政策实施后的斜率率为 - 0.766（<0.001），表明艾滋病相关死亡率呈下降趋势。中国“四免一关怀”政策的实施在免费艾滋病抗病毒治疗方面取得了显著进展。
