Klug S, Planas-Bohne F, Taylor D M
Kernforschungszentrum Karlsruhe, Institut für Genetik und Toxikologie, Karlsruhe, FRG.
Hum Toxicol. 1988 Nov;7(6):545-9. doi: 10.1177/096032718800700605.
The uptake of cadmium was studied in Chinese Hamster Ovary (CHO) cells. Cadmium accumulates rapidly against a concentration gradient and uptake is dependent on incubation temperature. The presence of serum or albumin results in a reduction in Cd uptake. Several substances known to influence certain metabolic steps of cell metabolism were used to influence Cd accumulation. Of these compounds, those that blocked the SH groups of the plasma membrane exerted the strongest influence. The effect of inhibitors of endocytosis was less pronounced.
在中国仓鼠卵巢（CHO）细胞中研究了镉的摄取情况。镉能逆浓度梯度快速积累，摄取量取决于孵育温度。血清或白蛋白的存在会导致镉摄取量减少。使用了几种已知会影响细胞代谢某些代谢步骤的物质来影响镉的积累。在这些化合物中，那些阻断质膜SH基团的化合物影响最强。内吞作用抑制剂的作用不太明显。
