Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.
Division of Infectious Diseases, Department of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.
PLoS One. 2020 Apr 16;15(4):e0231424. doi: 10.1371/journal.pone.0231424. eCollection 2020.
People who inject drugs (PWID) are at an increased risk for HIV infection due to injection and sexual risk behaviors. This study aims to examine PrEP knowledge, awareness, and willingness to be linked to PrEP services at a syringe services program (SSP), and examine the relationship between substance use and interest in PrEP linkage.
Data were collected using a cross-sectional survey of IDEA SSP clients in Miami, FL (N = 157). Based on reported substance injected, participants were classified into opioid-only injection or polysubstance injection. Socio-demographics and HIV risk were examined using Pearson's Chi-Squared analysis. Bivariate and multivariable logistic regression models were used to test for significant correlates of interest in PrEP linkage.
Only 28.3% of PWID surveyed had previously heard of PrEP. However, 57.2% were interested in receiving more information about PrEP. In the adjusted model, people with opioid-only use were significantly less likely to report interest in being linked to PrEP.
Knowledge, awareness, and interest in being linked to PrEP were low among PWID surveyed. No participants of the study were successfully linked to PrEP services through direct referrals. Further research is needed to examine low threshold service delivery of PrEP to PWID at SSPs.
由于注射和性行为风险，注射毒品者（PWID）感染艾滋病毒的风险增加。本研究旨在调查在注射毒品者服务项目（SSP）中，预防用药（PrEP）的知识、认识和接受意愿，并探讨物质使用与接受 PrEP 联系意愿之间的关系。
使用佛罗里达州迈阿密 IDEA SSP 客户的横断面调查收集数据（N=157）。根据报告的注射物质，参与者分为阿片类药物单一注射或多物质注射。使用 Pearson's Chi-Squared 分析检查社会人口统计学和艾滋病毒风险。使用双变量和多变量逻辑回归模型测试 PrEP 联系意愿的显著相关因素。
调查的 PWID 中只有 28.3% 以前听说过 PrEP。然而，57.2% 的人有兴趣了解更多关于 PrEP 的信息。在调整后的模型中，仅使用阿片类药物的人报告对接受 PrEP 联系的兴趣显著降低。
接受 PrEP 联系的知识、认识和意愿在接受调查的 PWID 中较低。研究中没有参与者通过直接转介成功联系到 PrEP 服务。需要进一步研究在 SSP 为 PWID 提供低门槛的 PrEP 服务。
