缅甸新生儿经皮胆红素时间特异性列线图
Hour-specific nomogram for transcutaneous Bilirubin in newborns in Myanmar.
机构信息
Department of Pediatrics, Faculty of Medicine, Kagawa University.
Department of Hygiene, Faculty of Medicine, Kagawa University, Kagawa, Japan.
出版信息
Pediatr Int. 2020 Sep;62(9):1049-1053. doi: 10.1111/ped.14251. Epub 2020 Sep 14.
BACKGROUND
Neonatal hyperbilirubinemia is a significant health problem in Myanmar, and the rate of kernicterus is also higher than in developed countries. Non-invasive methods for early detection and treatment of hyperbilirubinemia are urgently needed. In this study, we used transcutaneous bilirubin (TcB) measurements to develop an hour-specific TcB nomogram for the effective management of hyperbilirubinemia in Myanmar newborns.
METHODS
The bilirubin levels of neonates born in Central Women Hospital in Yangon, Myanmar were measured three times a day within 72 h after birth using a transcutaneous bilirubinometer. An hour-specific TcB nomogram was created based on the data.
RESULTS
Participants were 512 infants (287 boys, 225 girls) born in Central Women's Hospital in Yangon. The mean (±SD) gestational age was 38.4 ± 1.2 weeks; birthweight was 3078 ± 412 g. A total of 3,039 plots were obtained, and the TcB nomogram was created with smoothed percentile curves (97.5th, 50th, and 2.5th percentiles) for 0-72 h after birth.
CONCLUSIONS
An hour-specific TcB nomogram was successfully created to manage hyperbilirubinemia in Myanmar newborns.
背景
新生儿高胆红素血症是缅甸的一个重大健康问题，核黄疸的发病率也高于发达国家。迫切需要非侵入性的方法来早期检测和治疗高胆红素血症。在这项研究中，我们使用经皮胆红素（TcB）测量值为缅甸新生儿制定了一个小时特异性的 TcB 图表，以有效管理高胆红素血症。
方法
在缅甸仰光中央妇女医院出生的新生儿在出生后 72 小时内每天测量三次 TcB，使用经皮胆红素计。根据数据制定了一个小时特异性的 TcB 图表。
结果
参与者为 512 名婴儿（287 名男孩，225 名女孩），均在仰光中央妇女医院出生。平均（±SD）胎龄为 38.4±1.2 周；出生体重为 3078±412 克。共获得 3039 个数据点，为出生后 0-72 小时创建了 TcB 图表，具有平滑的百分位数曲线（97.5 百分位、50 百分位和 2.5 百分位）。
结论
成功为缅甸新生儿制定了一个小时特异性的 TcB 图表来管理高胆红素血症。
Zotero 插件