King's College London, Faculty of Life Sciences & Medicine, School of Cancer & Pharmaceutical Sciences, Cancer Prevention Group, London, UK.
J Med Screen. 2021 Jun;28(2):80-87. doi: 10.1177/0969141320918270. Epub 2020 Apr 16.
Introduction of new technologies into cervical screening programmes has allowed more efficient programmes with less resources. We present an overview of screening technologies introduced into the Cervical Screening Wales programme and their evolution over time.
Data from the programme's statistical report were used to evaluate its performance over a 17-year period between 2001/02 and 2017/18.
The introduction of liquid-based cytology has had a substantial impact on reducing inadequate sample rates and on increasing the positive predictive value of cytology. Inadequate rates have increased following the implementation of human papilloma virus testing as a triage test for cytology. Further knock-on effects on standard reporting ranges are expected following the introduction of human papilloma virus testing as the primary screening test. New performance standards have been introduced to better reflect the performance of the programme at a time when disease prevalence is expected to fall as women vaccinated against human papilloma virus reach screening age.
Improvements to this cervical cancer screening programme as illustrated through performance indicator ranges suggest a major role played by technology.
新技术在宫颈癌筛查项目中的引入使得资源利用更高效。我们介绍了引入到威尔士宫颈癌筛查项目中的筛查技术及其随时间的演变。
使用该项目统计报告中的数据,在 2001/02 至 2017/18 年的 17 年间评估其性能。
液基细胞学的引入对降低不充分样本率和提高细胞学的阳性预测值产生了重大影响。在将人乳头瘤病毒检测作为细胞学的分流试验实施后,不充分率有所增加。随着人乳头瘤病毒检测作为主要筛查试验的引入,预计对标准报告范围会产生进一步的连锁影响。随着接种人乳头瘤病毒疫苗的女性进入筛查年龄,预计疾病流行率将会下降,因此引入了新的性能标准,以更好地反映该项目的性能。
通过性能指标范围可以看出,这些宫颈癌筛查项目的改进表明技术发挥了重要作用。