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因合成大麻意外摄入溴敌隆中毒继发的弥散性血管内凝血

Disseminated Intravascular Coagulopathy Secondary to Unintentional Brodifacoum Poisoning via Synthetic Marijuana.

作者信息

Chan Abigail, Adashek Michael, Kang Julian, Medina Adriana

机构信息

Department of Internal Medicine, Sinai Hospital of Baltimore, Baltimore, MD, USA.

Department of Medical Oncology, Sinai Hospital of Baltimore, Baltimore, MD, USA.

出版信息

J Hematol. 2019 Mar;8(1):40-43. doi: 10.14740/jh486. Epub 2019 Mar 30.

DOI:10.14740/jh486
PMID:32300441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7153670/
Abstract

Recent evidence demonstrates a rising epidemic of unintentional brodifacoum poisoning associated with synthetic cannabinoid use. Synthetic cannabinoid use is on the rise because of its inexpensiveness as well as difficulty to screen and regulate. We present a rare case of severe coagulopathy and cardiac arrest secondary to synthetic cannabinoid use complicated by brodifacoum toxicity.

摘要

最近的证据表明,与合成大麻素使用相关的意外溴敌隆中毒呈上升趋势。由于合成大麻素价格低廉且难以筛查和监管,其使用正在增加。我们报告了一例罕见病例,该病例因合成大麻素使用并发溴敌隆毒性,继发严重凝血病和心脏骤停。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e80/7153670/beb770d3d2d4/jh-08-040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e80/7153670/beb770d3d2d4/jh-08-040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e80/7153670/beb770d3d2d4/jh-08-040-g001.jpg

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本文引用的文献

1
An Outbreak of Synthetic Cannabinoid-Associated Coagulopathy in Illinois.伊利诺伊州一起合成大麻素相关凝血功能障碍暴发事件。
N Engl J Med. 2018 Sep 27;379(13):1216-1223. doi: 10.1056/NEJMoa1807652.
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Retrospective Study of the Characteristics of Anticoagulant-Type Rodenticide Poisoning in Hong Kong.香港抗凝血型灭鼠剂中毒特征的回顾性研究。
J Med Toxicol. 2018 Sep;14(3):218-228. doi: 10.1007/s13181-018-0660-x. Epub 2018 Apr 23.
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Grass is not always greener: rodenticide exposure of a threatened species near marijuana growing operations.
草并非总是更绿:在大麻种植场附近受威胁物种接触灭鼠剂的情况。
BMC Res Notes. 2018 Feb 2;11(1):94. doi: 10.1186/s13104-018-3206-z.
4
A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus-A case report and review of the literature.一种棘手的情况:合成大麻素(香料)的使用与新发难治性癫痫持续状态——一例病例报告及文献综述
SAGE Open Med Case Rep. 2017 Dec 5;5:2050313X17745206. doi: 10.1177/2050313X17745206. eCollection 2017.
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Recovery of brodifacoum in vomitus following induction of emesis in dogs that had ingested rodenticide bait.对摄入杀鼠剂诱饵的犬只进行催吐后,呕吐物中溴敌隆的回收情况。
N Z Vet J. 2018 Jan;66(1):41-43. doi: 10.1080/00480169.2017.1379915. Epub 2017 Oct 11.
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Spice-y Kidney Failure: A Case Report and Systematic Review of Acute Kidney Injury Attributable to the Use of Synthetic Cannabis.香料致肾衰竭:一例报告及对合成大麻使用所致急性肾损伤的系统评价
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Acute Poisonings from Synthetic Cannabinoids - 50 U.S. Toxicology Investigators Consortium Registry Sites, 2010-2015.合成大麻素所致急性中毒——美国毒理学调查员联盟50个登记点,2010 - 2015年
MMWR Morb Mortal Wkly Rep. 2016 Jul 15;65(27):692-5. doi: 10.15585/mmwr.mm6527a2.
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The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures.超级华法林的新威胁:历史、检测、作用机制及应对措施
Ann N Y Acad Sci. 2016 Jun;1374(1):111-22. doi: 10.1111/nyas.13085. Epub 2016 May 31.
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Clin Toxicol (Phila). 2016;54(1):1-13. doi: 10.3109/15563650.2015.1110590. Epub 2015 Nov 15.
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Synthetic cannabinoids and acute kidney injury.合成大麻素与急性肾损伤
Proc (Bayl Univ Med Cent). 2015 Oct;28(4):475-7. doi: 10.1080/08998280.2015.11929313.