Srisung Weeraporn, Jamal Faisal, Prabhakar Sharma
Department of Internal Medicine (Srisung, Jamal, Prabhakar) and the Division of Nephrology (Jamal, Prabhakar), Texas Tech University Health Sciences Center, Lubbock, Texas.
Proc (Bayl Univ Med Cent). 2015 Oct;28(4):475-7. doi: 10.1080/08998280.2015.11929313.
Synthetic cannabinoids (SCB) are a family of chemicals that bind to cannabinoid receptors and cause psychoactive effects. Over the past few years, they have been increasingly used for recreational purposes, especially by young adults, and have been reported to have many adverse effects. Acute kidney injury (AKI) has been recently reported; the pathophysiology of SCB-induced AKI is unknown. We report three cases of AKI in the setting of SCB use. The peak serum creatinine levels ranged from 3.0 to 5.7 mg/dL; one patient required hemodialysis. SCB can induce AKI.
合成大麻素（SCB）是一类与大麻素受体结合并产生精神活性作用的化学物质。在过去几年中，它们越来越多地被用于娱乐目的，尤其是被年轻人使用，并且据报道有许多不良反应。最近有急性肾损伤（AKI）的报道；SCB诱导的AKI的病理生理学尚不清楚。我们报告了3例在使用SCB情况下发生AKI的病例。血清肌酐峰值水平在3.0至5.7mg/dL之间；1例患者需要进行血液透析。SCB可诱导AKI。
