Koh Bryant, Halliday Catriona, Chan Raymond
Department of Infectious Diseases and Microbiology, New South Wales Health Pathology, Royal Prince Alfred Hospital, Missenden Street, Camperdown, 2050, Australia.
Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR, New South Wales Health Pathology, Westmead Hospital, Hawkesbury Road, Westmead, 2145, Australia.
Med Mycol Case Rep. 2020 Apr 1;28:23-25. doi: 10.1016/j.mmcr.2020.03.007. eCollection 2020 Jun.
We report the case of a 54-year-old patient with central venous catheter related mixed candidaemia with and , who responded to line removal and anidulafungin therapy. Mixed candidaemia was detected on Candida chromogenic agar. Identification of the two isolates was confirmed by MALDI-TOF MS (Bruker). Antifungal susceptibility testing revealed different antifungal MICs. This is the first reported case of mixed candidaemia and outlines laboratory methodology to aid diagnosis and management.
我们报告了一例54岁患者,其患有与中心静脉导管相关的白色念珠菌和近平滑念珠菌混合血症,经拔除导管及使用阿尼芬净治疗后病情好转。在念珠菌显色琼脂上检测到混合念珠菌血症。通过基质辅助激光解吸电离飞行时间质谱(布鲁克公司)确认了两种分离株的鉴定。抗真菌药敏试验显示了不同的抗真菌最低抑菌浓度。这是首例报告的混合念珠菌血症病例,并概述了有助于诊断和管理的实验室方法。