免疫抑制患者的诺卡菌性骨髓炎。

Nocardia osteomyelitis in an immunosuppressed patient.

作者信息

Boulios Evangelos A, Konstantopoulou Pinelopi P, Bailas Georgios D, Klagkou Anastasia K, Tseliou Georgia C, Gkoulia Ioanna Z, Georgountzos Athanasios I

机构信息

Department of Rheumatology, Athens General Hospital «G. Gennimatas», Athens, Greece.

Department of Pediatric Surgery, General Maternity Hospital «Elena Venizelou», Athens, Greece.

出版信息

J Frailty Sarcopenia Falls. 2017 Dec 1;2(4):88-91. doi: 10.22540/JFSF-02-088. eCollection 2017 Dec.

DOI:10.22540/JFSF-02-088

PMID:32300686

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7155364/

Abstract

Osteomyelitis is an inflammation process of bone caused by a pathogenic microorganism and associated by edema, thrombosis of small vessels and eventually bone necrosis. Infection of bone occurs as a consequence of hematogenous dissemination of bacteria, invasion from a contiguous focuw of infection and skin breakdown. We report a case of lower limbs osteomyelitis due to Nocardia spp in a 68 years old man with Granulomatosis with Polyangiitis (GPA) during his treatment of underlying vasculitis. This case indicates considering rare pathogens in immunosuppressed patients.

摘要

骨髓炎是由病原微生物引起的骨炎症过程，伴有水肿、小血管血栓形成，最终导致骨坏死。骨感染是细菌血行播散、邻近感染灶侵袭和皮肤破损的结果。我们报告一例68岁患有肉芽肿性多血管炎（GPA）的男性在治疗潜在血管炎期间因诺卡菌属导致下肢骨髓炎的病例。该病例提示在免疫抑制患者中应考虑罕见病原体。