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慢性疼痛、心血管健康与相关药物使用在老年非裔美国人骨关节炎中的表现。

Chronic pain, cardiovascular health and related medication use in ageing African Americans with osteoarthritis.

机构信息

College of Nursing, The University of Florida, Gainesville, FL, USA.

Pain Research and Intervention Center of Excellence (PRICE), The University of Florida, Gainesville, FL, USA.

出版信息

J Clin Nurs. 2020 Jul;29(13-14):2675-2690. doi: 10.1111/jocn.15292. Epub 2020 May 5.

Abstract

AIM AND OBJECTIVES

To describe the (a) prevalence and perceptions of cardiovascular disease and related health conditions in African Americans with osteoarthritis pain, (b) their knowledge of cardiovascular safety of commonly prescribed analgesics for osteoarthritis and (c) frequency of high-risk analgesic use.

BACKGROUND

African Americans have more disabling osteoarthritis pain and an excessive burden of cardiovascular disease than any other US racial group. However, minimal research has investigated the relationship between chronic pain and cardiovascular disease and subsequent medication knowledge and use in African Americans. Consolidated Criteria for Reporting Qualitative and Srengthening the Reporting of Observational studies in Epidemiology checklists were followed.

DESIGN

A descriptive, secondary mixed-methods analysis.

METHODS

A convenience sample of 110 African American adults (50-94 years and older) completed surveys and individual qualitative interviews. Data were analysed using descriptive statistics, chi-square or Fisher's exact test, t test, Mann-Whitney U and a qualitative content analysis.

RESULTS

Hypertension was the most common cardiovascular condition reported, and African Americans with hypertension reported greater pain than those without. The survey questions revealed that most participants did not possess accurate knowledge about the appropriateness of analgesics in heart failure and other cardiovascular-related diseases; however, during the interviews, some did acknowledge a general understanding of the negative effects of some medications. Still, many older adults were taking nonsteroidal anti-inflammatory drugs despite having hypertension.

CONCLUSIONS

There was evidence of multimorbidity in our sample; based on our data, chronic osteoarthritis pain and hypertension are two highly comorbid conditions, suggesting a possible syndemic. More disparate is the lack of knowledge that African Americans possess as it relates to safe use of analgesic medications when cardiovascular disease is present.

RELEVANCE TO CLINICAL PRACTICE

Chronic pain and cardiovascular-related diseases are common and often co-occur and should be evaluated in all older adults, particularly African Americans. Both issues are important to manage, including the safe and appropriate use of medications, to prevent adverse effects.

摘要

目的和目标

描述(a)患有骨关节炎疼痛的非裔美国人中心血管疾病及相关健康状况的流行情况和认知,(b)他们对常用于治疗骨关节炎的常见镇痛剂的心血管安全性的了解,以及(c)高风险镇痛剂使用的频率。

背景

非裔美国人比任何其他美国种族群体都有更多的致残性骨关节炎疼痛和过重的心血管疾病负担。然而,很少有研究调查慢性疼痛与心血管疾病以及随后的药物知识和使用在非裔美国人中的关系。本研究遵循了定性和观察性研究报告的统一标准和强化报告规范清单。

设计

描述性、二次混合方法分析。

方法

采用便利抽样法,对 110 名非裔美国成年人(50-94 岁及以上)进行了问卷调查和个体定性访谈。使用描述性统计、卡方或 Fisher 精确检验、t 检验、Mann-Whitney U 检验和定性内容分析对数据进行分析。

结果

高血压是非裔美国人报告的最常见心血管疾病,且患有高血压的非裔美国人比未患有高血压的人报告有更严重的疼痛。调查问题显示,大多数参与者对心力衰竭和其他心血管相关疾病中镇痛药的适当性没有准确的了解;然而,在访谈中,一些人确实承认对某些药物的负面影响有一般的了解。尽管如此,许多老年人尽管患有高血压,仍在服用非甾体抗炎药。

结论

我们的样本中存在多种疾病共存的证据;根据我们的数据,慢性骨关节炎疼痛和高血压是两种高度共病的疾病,这表明可能存在一种综合征。更不同的是,非裔美国人缺乏与存在心血管疾病时安全使用镇痛药相关的知识。

临床相关性

慢性疼痛和心血管相关疾病很常见,且常同时发生,应在所有老年人中进行评估,特别是非裔美国人。这两个问题都很重要,包括管理药物的安全和适当使用,以预防不良影响。

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