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Immune function in hypopituitarism: time to reconsider?垂体功能减退症患者的免疫功能:是时候重新考虑了吗?
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COVID-19 患者经鼻内镜垂体腺瘤切除术:病例报告。

A COVID-19 Patient Who Underwent Endonasal Endoscopic Pituitary Adenoma Resection: A Case Report.

机构信息

Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Neurosurgery. 2020 Aug 1;87(2):E140-E146. doi: 10.1093/neuros/nyaa147.

DOI:10.1093/neuros/nyaa147
PMID:32302399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7188148/
Abstract

BACKGROUND AND IMPORTANCE

A pituitary adenoma patient who underwent surgery in our department was diagnosed with COVID-19 and 14 medical staff were confirmed infected later. This case has been cited several times but without accuracy or entirety, we feel obligated to report it and share our thoughts on the epidemic among medical staff and performing endonasal endoscopic surgery during COVID-19 pandemic.

CLINICAL PRESENTATION

The patient developed a fever 3 d post endonasal endoscopic surgery during which cerebrospinal leak occurred, and was confirmed with SARS-CoV-2 infection later. Several medical staff outside the operating room were diagnosed with COVID-19, while the ones who participated in the surgery were not.

CONCLUSION

The deceptive nature of COVID-19 results from its most frequent onset symptom, fever, a cliché in neurosurgery, which makes it hard for surgeons to differentiate. The COVID-19 epidemic among medical staff in our department was deemed as postoperative rather than intraoperative transmission, and attributed to not applying sufficient personal airway protection. Proper personal protective equipment and social distancing between medical staff contributed to limiting epidemic since the initial outbreak. Emergency endonasal endoscopic surgeries are feasible since COVID-19 is still supposed to be containable when the surgeries are performed in negative pressure operating rooms with personal protective equipment and the patients are kept under quarantine postoperatively. However, we do not encourage elective surgeries during this pandemic, which might put patients in conditions vulnerable to COVID-19.

摘要

背景与重要性

我科曾有 1 例垂体腺瘤术后患者被诊断为 COVID-19,之后有 14 名医务人员确诊感染。该病例曾被多次引用,但不够准确和完整,我们有责任进行报告,并就 COVID-19 大流行期间医务人员的疫情和鼻内镜手术相关问题分享我们的观点。

临床表现

该患者在鼻内镜手术后第 3 天出现发热,期间发生脑脊液漏,后确诊为 SARS-CoV-2 感染。多名不在手术室的医务人员被诊断为 COVID-19,而参与手术的医务人员没有感染。

结论

COVID-19 的隐匿性来自于其最常见的首发症状发热,这在神经外科中很常见,使外科医生难以区分。我们科室的医务人员 COVID-19 疫情被认为是术后而非术中传播,原因是没有充分应用个人气道保护措施。适当的个人防护设备和医务人员之间的社交距离有助于限制疫情的初始爆发。自 COVID-19 疫情爆发以来,在负压手术室中使用个人防护设备和对患者进行术后隔离的情况下,可行开展紧急鼻内镜手术。然而,我们不鼓励在大流行期间进行选择性手术,因为这可能会使患者处于 COVID-19 的易感状态。