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癌症神经科学新兴领域路线图。

Roadmap for the Emerging Field of Cancer Neuroscience.

机构信息

Departments of Neurology & Neurological Sciences, Pediatrics, Pathology, Neurosurgery, and Psychiatry & Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

出版信息

Cell. 2020 Apr 16;181(2):219-222. doi: 10.1016/j.cell.2020.03.034.

DOI:10.1016/j.cell.2020.03.034
PMID:32302564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7286095/
Abstract

Mounting evidence indicates that the nervous system plays a central role in cancer pathogenesis. In turn, cancers and cancer therapies can alter nervous system form and function. This Commentary seeks to describe the burgeoning field of "cancer neuroscience" and encourage multidisciplinary collaboration for the study of cancer-nervous system interactions.

摘要

越来越多的证据表明神经系统在癌症发病机制中起着核心作用。反过来,癌症和癌症治疗也可以改变神经系统的形态和功能。本评论旨在描述“癌症神经科学”这一新兴领域,并鼓励开展多学科合作,以研究癌症与神经系统的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34af/7286095/226b28bef61c/nihms-1594317-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34af/7286095/226b28bef61c/nihms-1594317-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34af/7286095/226b28bef61c/nihms-1594317-f0001.jpg

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Glutamatergic synaptic input to glioma cells drives brain tumour progression.谷氨酸能突触输入到神经胶质细胞瘤驱动脑肿瘤的进展。
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