Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.
Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Nat Cell Biol. 2022 Oct;24(10):1454-1460. doi: 10.1038/s41556-022-00978-w. Epub 2022 Sep 12.
The biological and pathological importance of mutual interactions between the nervous system and cancer have become increasingly evident. The emerging field of cancer neuroscience aims to decipher key signalling factors of cancer-nervous system crosstalk and to exploit these modulators as targets for improved anticancer therapies. Here we discuss the key achievements in cancer neuroscience research, inspire further interactions on a variety of related research topics, and provide a roadmap for future studies.
神经系统和癌症之间相互作用的生物学和病理学重要性已经变得越来越明显。癌症神经科学这一新兴领域旨在破译癌症-神经系统相互作用的关键信号因子，并将这些调节剂作为提高抗癌疗法的靶点加以利用。在这里，我们讨论了癌症神经科学研究的主要成果，激发了对各种相关研究课题的进一步互动，并为未来的研究提供了路线图。
