Department of neurology, university of Parakou, 03 BP, 10 Parakou, Benin; Clinic of Neurology, University Teaching Hospital of Parakou, Benin; GEIST, UMR-1094 (1) Inserm, UMR-1094, tropical neuroepidemiology, Institute of epidemiology and tropical neurology, CHU of Limoges, university of Limoges, 87000 Limoges, France.
Clinic of Neurology, University Teaching Hospital of Parakou, Benin.
Rev Neurol (Paris). 2020 Dec;176(10):839-845. doi: 10.1016/j.neurol.2020.02.005. Epub 2020 Apr 14.
Stroke is a major public health problem with a high burden in Sub-Saharan Africa. We aimed to determine the prevalence of stroke in Titirou in Parakou.
It was a cross-sectional study using a door-to-door survey in Titirou (Parakou) from 15 march to 15 October 2016 and included 4671 adults. We did a two stages survey. In the first stage the World Health Organization (WHO) tool for the diagnosis of stroke in community was used. In the second phase all suspected cases underwent neurological exam and sometimes brain CT-scan. The WHO definition was used for the diagnosis of stroke. We recorded the socio-demographic data and the vascular risk factors. The prevalence was standardized on age according to the WHO type population. Multiple logistic regression was done to identify associated factors and estimate the adjusted prevalence ratio (aPR) and their 95% confidence interval (CI).
The mean age of the subjects was 27.7±12.9 years with a sex ratio of 0.97. After screening 161 were suspected and 54 confirmed cases, the overall prevalence of stroke in Titirou was 1.156 per 100,000 inhabitants [95% CI: 0.850 to 1.426]. The age-standardized prevalence of stroke was 3223 cases per 100,000 inhabitants. The associated factors were age (aPR 1.7 [1.5-1.9] for 10 years), history of hypertension (aPR: 64.8 [46.1-108.9]), diabetes mellitus (aPR: 4.5 [1.6-12.3]), low consumption of fruits and vegetables (aPR: 2.3 [1.2-4.4]), history of heart disease (aPR: 6.0 [2.6-13.7]), family history of stroke (PR: 4.6 [2.1-10.0]). Among the 54 subjects who had a stroke 10 were able to perform the brain CT-Scan: 40% were hemorrhagic and 60% ischemic stroke.
Our study showed a high prevalence of stroke in Titirou and suggested urgent action for prevention.
中风是撒哈拉以南非洲地区的一个主要公共卫生问题，负担沉重。我们旨在确定帕拉库的蒂蒂鲁中风的患病率。
这是一项横断面研究，于 2016 年 3 月 15 日至 10 月 15 日在蒂蒂鲁（帕拉库）进行了逐户调查，共纳入 4671 名成年人。我们进行了两阶段调查。第一阶段使用世界卫生组织（WHO）社区中风诊断工具。在第二阶段，所有疑似病例均接受了神经系统检查，有时还进行了脑部 CT 扫描。采用世界卫生组织的定义诊断中风。我们记录了社会人口统计学数据和血管危险因素。根据世界卫生组织人口类型对年龄进行标准化，计算患病率。采用多因素逻辑回归分析确定相关因素，并估计调整后的患病率比（aPR）及其 95%置信区间（CI）。
受试者的平均年龄为 27.7±12.9 岁，性别比为 0.97。经筛查，有 161 例疑似病例，54 例确诊病例，蒂蒂鲁的中风总患病率为每 10 万人 1.156 例[95%CI：0.850 至 1.426]。年龄标准化的中风患病率为每 10 万人 3223 例。相关因素为年龄（每增加 10 岁，aPR 为 1.7[1.5-1.9]）、高血压史（aPR：64.8[46.1-108.9]）、糖尿病（aPR：4.5[1.6-12.3]）、水果和蔬菜摄入量低（aPR：2.3[1.2-4.4]）、心脏病史（aPR：6.0[2.6-13.7]）、中风家族史（PR：4.6[2.1-10.0]）。在 54 例中风患者中，有 10 例能够进行脑部 CT 扫描：40%为出血性，60%为缺血性中风。
我们的研究表明，蒂蒂鲁中风的患病率很高，表明急需采取预防措施。
