Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 1070 Arastradero Rd. Ste 200, Palo Alto, CA, USA.
Addiction. 2020 Jul;115(7):1306-1307. doi: 10.1111/add.15048. Epub 2020 Apr 18.
Larence et al.’s findings have key implications for XR-buprenorphine guidelines as it becomes available internationally. These are to embrace less-onerous dosing schedules, to consider incorporating into standard-of-care an option to supplement with transmucosal buprenorphine between injections, and to investigate what possibilities XR-buprenorphine opens up for patients wanting to taper off opioid agonist treatment.
劳伦斯等人的研究结果对 XR-丁丙诺啡国际应用指南具有重要意义。这些建议包括采用更少侵入性的给药方案,考虑在标准治疗中加入一种选择,即在注射之间用透黏膜丁丙诺啡进行补充,并研究 XR-丁丙诺啡为希望逐渐减少阿片类激动剂治疗的患者提供了哪些可能性。