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用电视网膜图和增量阈值数据检验关于发育的假设。

Testing hypotheses about development with electroretinographic and incremental-threshold data.

作者信息

Hood D C

机构信息

Columbia University, New York, New York 10027.

出版信息

J Opt Soc Am A. 1988 Dec;5(12):2159-65. doi: 10.1364/josaa.5.002159.

DOI:10.1364/josaa.5.002159
PMID:3230485
Abstract

Electroretinographic (ERG) and incremental-threshold [threshold-versus-intensity (tvi)] data have been used to infer mechanisms of development. For a hypothesis about development to be tested, the hypothesis must be specified in the context of a model of the adult visual system. Here, published ERG and tvi data obtained from infants are analyzed in the context of models with two sites. The first site in each of these models has the properties of the rod receptors. By a combination of hypotheses about development and these models, other hypotheses are considered. Taken together, the ERG and tvi data are consistent with a scheme in which developmental changes during the first 18 weeks occur largely, if not entirely, in the retina. Some of these changes may be receptoral in origin. The need for explicit adult models and explicit developmental hypotheses is emphasized.

摘要

视网膜电图(ERG)和递增阈值[阈值与强度(tvi)]数据已被用于推断发育机制。要检验一个关于发育的假设,该假设必须在成人视觉系统模型的背景下进行明确阐述。在此,从婴儿身上获得的已发表的ERG和tvi数据在具有两个位点的模型背景下进行分析。这些模型中的每个第一个位点都具有视杆感受器的特性。通过结合关于发育的假设和这些模型,考虑了其他假设。总体而言,ERG和tvi数据与一种方案一致,即前18周的发育变化如果不是完全,至少在很大程度上发生在视网膜中。其中一些变化可能起源于感受器。强调了明确成人模型和明确发育假设的必要性。

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