果蝇中的囊泡神经递质转运体。
Vesicular neurotransmitter transporters in Drosophila melanogaster.
机构信息
Hatos Center for Neuropharmacology, Department of Psychiatry and Biobehavioral Sciences and Semel Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Departments of Psychiatry and Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
Biochim Biophys Acta Biomembr. 2020 Dec 1;1862(12):183308. doi: 10.1016/j.bbamem.2020.183308. Epub 2020 Apr 17.
Abstract
Drosophila melanogaster express vesicular transporters for the storage of neurotransmitters acetylcholine, biogenic amines, GABA, and glutamate. The large array of powerful molecular-genetic tools available in Drosophila enhances the use of this model organism for studying transporter function and regulation.
摘要
黑腹果蝇表达囊泡转运蛋白以储存神经递质乙酰胆碱、生物胺、GABA 和谷氨酸。果蝇中大量可用的强大的分子遗传工具增强了这种模式生物在研究转运蛋白功能和调节中的应用。
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