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果蝇成体大脑:结构、功能及资源概述 图形综述论文

The Drosophila adult brain: short overview of structure, function, and resources Graphical Review Paper.

作者信息

Robinson J Wesley, Bechard Abigail T, Frame Ariel K, Evans Micah R, Atheby Angeline-Claudia, Sharma Shaunik, Lawal Hakeem O, Simon Anne F

机构信息

Biology Department, Faculty of Science, University of Western Ontario, Canada.

School of Biosciences, University of Sheffield, United Kingdom.

出版信息

Curr Res Insect Sci. 2025 May 15;7:100113. doi: 10.1016/j.cris.2025.100113. eCollection 2025.

Abstract

This short review is targeted at researchers new to the Drosophila model (thereafter: a Drosophilist) in the field of neuroscience. We aim to provide an introductory overview of our current understanding of the adult (thereafter: Drosophila) brain, its structures, circuitry, and associated behaviours, as well as links to additional resources for more in-depth information. Throughout this overview, we mostly provide references to seminal review articles instead of the original research articles that are thoroughly provided within each review. We do not claim to present an exhaustive exploration of this rapidly expanding field, or of its history. Rather, the field currently lacks a short and simple up-to-date guide to the adult Drosophila brain. Finally, even though connectomes for the full larval brain and the adult ventral nerve cord have recently been made available, we are restricting our focus to the adult brain.

摘要

本简短综述针对神经科学领域刚接触果蝇模型的研究人员(以下简称:果蝇研究者)。我们旨在对目前关于成年果蝇大脑(以下简称:果蝇)的认识、其结构、神经回路、相关行为,以及获取更多深入信息的其他资源链接,提供一个入门概述。在本概述中,我们大多引用了具有开创性的综述文章,而非每篇综述中详尽列出的原始研究文章。我们并不声称对这个迅速发展的领域或其历史进行了详尽的探索。相反,该领域目前缺乏一本关于成年果蝇大脑的简短且最新的指南。最后,尽管最近已经有了完整幼虫大脑和成年腹神经索的连接组,但我们的重点仍局限于成年大脑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60de/12159932/75ec35174958/gr1.jpg

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