Costabile Ferdinando, Donnarumma Marianna, Piscosquito Arianna, Ingenito Concetta, Iuliucci Michela Rosaria, Buonerba Carlo, Di Lorenzo Giuseppe, Di Trolio Rossella
Oncolgy Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.
Associazione O.R.A.-Oncology Research Assistance, Somma Vesuviana, Italy.
Case Rep Oncol. 2023 Sep 19;16(1):935-938. doi: 10.1159/000531843. eCollection 2023 Jan-Dec.
Nasal vestibule squamous cell carcinoma (SCC) is a rare malignancy with limited treatment options. This case report presents an 83-year-old female with SCC of the nasal vestibule who was ineligible for surgery or radiotherapy due to various factors. The patient was successfully treated with cemiplimab, a systemic anti-PD-1 antibody, resulting in a remarkable tumor reduction without any observed side effects. This is the first reported case of nasal vestibule SCC treated with cemiplimab, highlighting its potential as a promising therapeutic option.
鼻前庭鳞状细胞癌（SCC）是一种罕见的恶性肿瘤，治疗选择有限。本病例报告介绍了一名83岁的鼻前庭鳞状细胞癌女性患者，由于各种因素，她不符合手术或放疗的条件。该患者接受了西妥昔单抗（一种全身性抗PD-1抗体）治疗并取得成功，肿瘤显著缩小，且未观察到任何副作用。这是首例报道使用西妥昔单抗治疗鼻前庭鳞状细胞癌的病例，突出了其作为一种有前景的治疗选择的潜力。
