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鼻填塞治疗鼻出血:疗效预测因素。

Nasal Packs for Epistaxis: Predictors of Success.

出版信息

Clin Otolaryngol. 2020 Sep;45(5):659-666. doi: 10.1111/coa.13555. Epub 2020 Jun 5.

Abstract

OBJECTIVES

To investigate factors affecting the haemostatic success of non-dissolvable intranasal packs in the management of acute epistaxis presenting to the emergency department (ED).

DESIGN

Prospective cohort study.

SETTING

A nationwide prospective audit examining epistaxis management at 113 sites in the UK over a 30-day period.

PARTICIPANTS

Patients 16 years or older, presenting to the ED with acute epistaxis managed with non-dissolvable intranasal packs.

MAIN OUTCOME MEASURES

The primary outcome was pack success, defined as successful haemostasis following nasal pack removal, not requiring further packing or surgical intervention or interventional radiology.

RESULTS

A cohort of 969 patients presented with epistaxis to the ED, with nasal packs being inserted in 54.4% by ED staff and by ENT in a further 18.9%. Overall, nasal packs were successful in 87.5%. Longer duration packs (≥21 hours) were more successful than shorter-duration packs (89.9% vs. 84.3%, χ P = .028). A patient survey supported longer packing duration. The most significant predictors of treatment failure were shorter packing duration (Odds Ratio (OR) = 2.3; 95% Confidence Interval (CI) = 1.4-3.8), alongside ischaemic heart disease (OR = 1.9; 95% CI = 1.1-3.3), normal admission haemoglobin (OR = 2.0; 95% CI = 1.2-3.4) and no attempt at cautery following pack removal (OR = 2.5; 95% CI = 1.4-4.2).

CONCLUSIONS

The majority of epistaxis patients are packed by the ED prior to referral to ENT. Once inserted, nasal packs are highly successful, with data supporting the British Rhinological Society guidance of maintaining nasal packs for around 24 hours. Further work is needed to explore alternatives to non-dissolvable intranasal packs to improve patient experience in epistaxis.

摘要

目的

研究影响急诊科(ED)急性鼻出血患者使用不可溶解鼻腔填塞物止血成功的因素。

设计

前瞻性队列研究。

地点

在英国的 113 个地点进行了为期 30 天的前瞻性审核,以检查鼻出血的管理情况。

参与者

年龄在 16 岁及以上的患者,因急性鼻出血就诊于 ED,并使用不可溶解鼻腔填塞物进行治疗。

主要观察指标

主要结局为填塞物成功,定义为鼻腔填塞物取出后止血成功,无需再次填塞、手术干预或介入放射学治疗。

结果

969 例患者因鼻出血就诊于 ED,其中 54.4%由 ED 工作人员,18.9%由耳鼻喉科医生插入鼻腔填塞物。总体而言,鼻腔填塞物的成功率为 87.5%。较长时间(≥21 小时)的填塞物比短时间(84.3%,χ P = 0.028)的填塞物更成功。患者调查支持更长的填塞时间。治疗失败的最显著预测因素是填塞时间较短(优势比(OR)= 2.3;95%置信区间(CI)= 1.4-3.8),以及缺血性心脏病(OR = 1.9;95% CI = 1.1-3.3)、正常入院时血红蛋白(OR = 2.0;95% CI = 1.2-3.4)和填塞物取出后未尝试烧灼(OR = 2.5;95% CI = 1.4-4.2)。

结论

大多数鼻出血患者在转至耳鼻喉科医生之前在 ED 进行填塞。一旦插入,鼻腔填塞物非常成功,数据支持英国鼻科学会的指导,即保持鼻腔填塞物约 24 小时。需要进一步研究替代不可溶解鼻腔填塞物的方法,以改善鼻出血患者的体验。

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