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[骨传导振动及声诱发眼肌源性电位的频率特性]

[Frequency properties of bone-conducted vibration and sound-induced ocular evoked myogenic potential].

作者信息

Lin Y, Zhong B, Fan X Q, Wang M J, Liu J W, Guo Q, Zha D J

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, First Affiliated Hospital, Military Air Force Medical University, Xi'an 710032, China.

National Institute of Metrology, China, Beijing 100029, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr 7;55(4):338-343. doi: 10.3760/cma.j.cn115330-20191021-00639.

Abstract

The present study was to compare the frequency characteristics of bone- conducted vibration (BCV) and air-conducted sound-induced ocular vestibular evoked myogenic potential(oVEMP) with different stimulation settings, so as to select an optimal setting. Bruel and Kjaer artificial mastoid was used to calibrate bone vibrator, the mini-shaker. The outputspectrum and transient waveform were recorded when the input frequency was set at different frequencies and data were further analyzed to get the peake quivalent force level value of the output vibration. oVEMP was recorded as we previously reported with normal young adults. Response prevalence, latency, wave interval, amplitude, amplitude ratio, and bilateral amplitude asymmetry ratio were recorded and analyzed. SPSS 24.0 software was used for statistical analysis. Output peak equivalent force level increased as the intensity of primary input stimulation increased at certain frequency,while it decreased as the frequency of primary input stimulation increased at certain intensity. Peak equivalent force level of 500 Hz tone burst (1-2-1) input stimulation was greatest as 139.8 dB when using mini-shaker for vibration stimulation,even greater when using bone conductor B-71.Twenty subjects were elicited with normal oVEMP with N1 and P1 waves in both ears using air-conducted stimulation or bone-conducted vibration.The response rate in these subjects was 95% and 100% respectively. The latency of N1 was (11.33±1.35) ms and (10.14±0.38) ms, latency of P1 was (16.24±1.56) ms and (15.65±1.19) ms, interval N1-P1 was (4.59±1.26) ms and (5.55±0.81) ms, symmetry coefficient was 12.22%[5.50%,21.85%] and 8.74%[3.37%,14.08%], amplitude was 3.07[2.05,4.43] μV and 3.07[2.05,4.43] μV in sound and bone conducted vibration group, respectively. The latency of N1, latency of P1, interval N1-P1, symmetry coefficient and n1-P1 amplitude of BC-oVEMP were different statistically (all 0.05). 500 Hz 45 dB input stimulation setting is the optimal parameter for BC-oVEMP. BC-oVEMP can be recorded simply, safely and quickly in normal young people, thus it is a clinically practical way of measuring utricular function.

摘要

本研究旨在比较不同刺激设置下骨传导振动(BCV)和气传导声音诱发的眼前庭诱发肌源性电位(oVEMP)的频率特性,以选择最佳设置。使用Bruel和Kjaer人工乳突对小型振动器骨振动器进行校准。当输入频率设置为不同频率时,记录输出频谱和瞬态波形,并进一步分析数据以获得输出振动的峰值等效作用力水平值。oVEMP的记录方法与我们之前对正常年轻人的报道相同。记录并分析反应发生率、潜伏期、波间期、振幅、振幅比和双侧振幅不对称比。使用SPSS 24.0软件进行统计分析。在一定频率下,输出峰值等效作用力水平随初级输入刺激强度的增加而增加,而在一定强度下,随初级输入刺激频率的增加而降低。当使用小型振动器进行振动刺激时,500Hz短纯音(1-2-1)输入刺激的峰值等效作用力水平最大,为139.8dB,使用骨传导器B-71时更大。20名受试者通过气传导刺激或骨传导振动双耳引出具有N1和P1波的正常oVEMP。这些受试者的反应率分别为95%和100%。声音组和骨传导振动组中,N1潜伏期分别为(11.33±1.35)ms和(10.14±0.38)ms,P1潜伏期分别为(16.24±1.56)ms和(15.65±1.19)ms,N1-P1间期分别为(4.59±1.26)ms和(5.55±0.81)ms,对称系数分别为12.22%[5.50%,21.85%]和8.74%[3.37%,14.08%],振幅分别为3.07[2.05,4.43]μV和3.07[2.05,4.43]μV。BC-oVEMP的N1潜伏期、P1潜伏期、N1-P1间期、对称系数和N1-P1振幅在统计学上存在差异(均P<0.05)。500Hz 45dB输入刺激设置是BC-oVEMP的最佳参数。在正常年轻人中,BC-oVEMP可以简单、安全且快速地记录,因此它是一种临床上实用的测量球囊功能的方法。

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