Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Maxim Integrated Products Inc., Chandler, AZ 85225, USA.
Exp Biol Med (Maywood). 2020 Jun;245(11):964-969. doi: 10.1177/1535370220920540. Epub 2020 Apr 19.
Early availability of the sequence, the genetic material of SARS-CoV-2 (the virus that causes COVID-19), has prompted efforts towards identifying a safe and effective vaccine in the current public health emergency. To that end, understanding the pathophysiology of disease is crucial for scientists around the world. Since conventional vaccine development and manufacturing may take several years, it is important to think about alternative strategies that we could use to mitigate imminent catastrophe. We hope that this article will open up new avenues and provide insights that could potentially save hundreds of lives affected by COVID-19.
序列的早期获得,即引发 COVID-19 的 SARS-CoV-2 病毒的遗传物质,促使人们在当前的公共卫生紧急情况下努力识别安全有效的疫苗。为此,了解疾病的病理生理学对于全世界的科学家来说至关重要。由于常规疫苗的开发和制造可能需要数年时间,因此考虑使用其他策略来减轻迫在眉睫的灾难非常重要。我们希望本文能开辟新途径并提供潜在的见解,从而有可能拯救数以百计受到 COVID-19 影响的生命。