TGSE BLADE DWI 与 RESOLVE DWI 诊断胆脂瘤的性能比较。
Performance of TGSE BLADE DWI compared with RESOLVE DWI in the diagnosis of cholesteatoma.
机构信息
Department of Radiology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Scientific Marketing, Siemens Healthcare, Shanghai, China.
出版信息
BMC Med Imaging. 2020 Apr 19;20(1):40. doi: 10.1186/s12880-020-00438-7.
BACKGROUND
Based on its high resolution in soft tissue, MRI, especially diffusion-weighted imaging (DWI), is increasingly important in the evaluation of cholesteatoma. The purpose of this study was to evaluate the role of the 2D turbo gradient- and spin-echo (TGSE) diffusion-weighted (DW) pulse sequence with the BLADE trajectory technique in the diagnosis of cholesteatoma at 3 T and to qualitatively and quantitatively compare image quality between the TGSE BLADE and RESOLVE methods.
METHOD
A total of 42 patients (23 males, 19 females; age range, 7-65 years; mean, 40.1 years) with surgically confirmed cholesteatoma in the middle ear were enrolled in this study. All patients underwent DWI (both a prototype TGSE BLADE DWI sequence and the RESOLVE DWI sequence) using a 3-T scanner with a 64-channel brain coil. Qualitative imaging parameters (imaging sharpness, geometric distortion, ghosting artifacts, and overall imaging quality) and quantitative imaging parameters (apparent diffusion coefficient [ADC], signal-to-noise ratio [SNR], contrast, and contrast-to-noise ratio [CNR]) were assessed for the two diffusion acquisition techniques by two independent radiologists.
RESULT
A comparison of qualitative scores indicated that TGSE BLADE DWI produced less geometric distortion, fewer ghosting artifacts (P < 0.001) and higher image quality (P < 0.001) than were observed for RESOLVE DWI. A comparison of the evaluated quantitative image parameters between TGSE and RESOLVE showed that TGSE BLADE DWI produced a significantly lower SNR (P < 0.001) and higher parameter values (both contrast and CNR (P < 0.001)) than were found for RESOLVE DWI. The ADC (P < 0.001) was significantly lower for TGSE BLADE DWI (0.763 × 10 mm/s) than RESOLVE DWI (0.928 × 10 mm/s).
CONCLUSION
Compared with RESOLVE DWI, TGSE BLADE DWI significantly improved the image quality of cholesteatoma by reducing magnetic sensitive artifacts, distortion, and blurring. TGSE BLADE DWI is more valuable than RESOLVE DWI for the diagnosis of small-sized (2 mm) cholesteatoma lesions. However, TGSE BLADE DWI also has some disadvantages: the whole image intensity is slightly low, so that the anatomical details of the air-bone interface are not shown well, and this shortcoming should be improved in the future.
背景
基于其在软组织方面的高分辨率，磁共振成像（MRI），尤其是扩散加权成像（DWI），在胆脂瘤的评估中变得越来越重要。本研究的目的是评估在 3T 下，二维涡轮梯度回波和自旋回波（TGSE）扩散加权（DW）脉冲序列与叶片轨迹技术在胆脂瘤诊断中的作用，并对 TGSE 叶片和 RESOLVE 方法的图像质量进行定性和定量比较。
方法
本研究共纳入 42 例（23 例男性，19 例女性；年龄 7-65 岁；平均 40.1 岁）经手术证实的中耳胆脂瘤患者。所有患者均在 3T 扫描仪上使用 64 通道脑线圈进行 DWI（包括原型 TGSE 叶片 DW 序列和 RESOLVE DWI 序列）。两位独立的放射科医生评估了两种扩散采集技术的定性成像参数（成像锐度、几何变形、鬼影伪影和整体成像质量）和定量成像参数（表观扩散系数[ADC]、信噪比[SNR]、对比度和对比噪声比[CNR]）。
结果
定性评分比较表明，与 RESOLVE DWI 相比，TGSE 叶片 DW 产生的几何变形更小，鬼影伪影更少（P < 0.001），图像质量更高（P < 0.001）。与 RESOLVE 相比，TGSE 和 RESOLVE 之间的定量图像参数比较表明，TGSE 叶片 DW 产生的 SNR 明显更低（P < 0.001），参数值（对比度和 CNR 均更高（P < 0.001））。与 RESOLVE DWI 相比，TGSE 叶片 DW 的 ADC 值明显更低（0.763×10 mm/s）。
结论
与 RESOLVE DWI 相比，TGSE 叶片 DW 通过减少磁敏感伪影、变形和模糊显著改善了胆脂瘤的图像质量。与 RESOLVE DWI 相比，TGSE 叶片 DW 对诊断小尺寸（2mm）胆脂瘤病变更有价值。然而，TGSE 叶片 DW 也有一些缺点：整体图像强度略低，因此空气-骨界面的解剖细节显示不佳，这一缺点在未来应加以改进。
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