抗生素的使用与耐药性：对黎巴嫩大学生知识、态度和实践（KAP）的空前评估。
Antibiotic use and resistance: an unprecedented assessment of university students' knowledge, attitude and practices (KAP) in Lebanon.
机构信息
Department of Biological and Chemical Sciences, School of Arts and Sciences, Lebanese International University, Beirut, Lebanon.
Department of Biomedical Sciences, School of Arts and Sciences, Lebanese International University, Beirut, Lebanon.
出版信息
BMC Public Health. 2020 Apr 19;20(1):535. doi: 10.1186/s12889-020-08676-8.
BACKGROUND
The emergence and spread of pathogenic bacteria that is resistant to antibiotics has become a major public health concern. The incorrect prescription, inappropriate consumption and excess use of antimicrobial drugs, specifically antibiotics, are possibly the main factors contributing to the widespread of antibiotic resistant bacteria. This study aims to evaluate the knowledge, attitude and practices (KAP) towards the use of antibiotics as well as their resistance among Lebanese university students in health and non-health related majors.
METHODS
This cross-sectional study was conducted between May and June 2019 in Beirut (Lebanon) in which 750 students completed a questionnaire made up of four dimensions: Socio-demographic characteristics, 3 questions; assessment of knowledge, attitude and practices, 7, 10 and 1 question, respectively. The data was collected in spreadsheets and analysed with descriptive statistics. The difference in mean scores in each of the knowledge, attitude and practices dimensions between health and non-health related major students was analysed using t-student tests and the difference in percentages using chi-square tests.
RESULTS
Almost 78% of respondents from the health related majors scored high knowledge compared to only 41% of non-health related majors (mean = 4.26; standard error = 0.05 versus mean = 3.41; standard error = 0.13, respectively). The attitude score of the health related major students (35.42%) was positive and more satisfactory compared to the non-health related students (7.32%); (mean = 9.34; standard error = 0.05 versus mean = 9.10; standard error = 0.21, respectively). However, the difference in the scores of attitudes was not statistically significant.
CONCLUSIONS
Interventions to promote awareness in this area should focus more students in on non-health related majors.
背景
具有抗药性的致病细菌的出现和传播已成为主要的公共卫生关注点。抗菌药物（特别是抗生素）的不正确处方、不当使用和过度使用可能是导致抗生素耐药细菌广泛传播的主要因素。本研究旨在评估黎巴嫩医学生和非医学生对抗生素使用及其耐药性的知识、态度和实践（KAP）。
方法
这是一项横断面研究，于 2019 年 5 月至 6 月在贝鲁特（黎巴嫩）进行，共有 750 名学生完成了一份由四个部分组成的问卷：社会人口统计学特征、3 个问题；知识、态度和实践评估，分别为 7、10 和 1 个问题。数据以电子表格形式收集，并进行描述性统计分析。使用 t 检验分析健康相关专业和非健康相关专业学生在知识、态度和实践维度上的平均得分差异，使用卡方检验分析百分比差异。
结果
近 78%的健康相关专业学生的知识得分较高，而非健康相关专业学生的知识得分仅为 41%（均值=4.26；标准误=0.05 与均值=3.41；标准误=0.13，分别）。健康相关专业学生的态度得分（35.42%）较非健康相关专业学生（7.32%）更为积极和满意（均值=9.34；标准误=0.05 与均值=9.10；标准误=0.21，分别）。然而，态度得分的差异无统计学意义。
结论
在这方面的干预措施应更多地关注非医学生。
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