Heryumani Sulandjari J C P, Chairunnisa Afina Zahra, Alhasyimi Ananto Ali
Department of Orthodontics, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Java, Indonesia.
Contemp Clin Dent. 2019 Jul-Sep;10(3):452-456. doi: 10.4103/ccd.ccd_740_18.
Patients with fixed orthodontic encounter problems in cleaning their teeth and mouths. Dental plaque tends to accumulate on wires, brackets, and surfaces between bonding materials and brackets. Plaque accumulation increases the risks of decalcification, caries, and gingivitis. Chitosan extract is a potential antibacterial agent and inhibitor of dental plaque formation. This study aims to assess the effectiveness of chitosan-containing dentifrice in decreasing plaque accumulation in patients with fixed orthodontic appliances.
This was a prospective, randomized, double-blind study which involved 32 samples (randomly allocated to the control and chitosan groups, after the power of the study was considered) from patients with orthodontic appliances undergoing the last stage of fixed active orthodontic treatment. Plaque accumulation before and after dentifrice use was measured using a plaque index according to O'leary, before and after using toothpaste within 5 days. The patients were instructed to brushing with chitosan-containing dentifrice and chitosan-free dentifrice as a control. Washout period that needed between brushing with chitosan-containing dentifrice and chitosan-free dentifrice as a control was 7 days. Each mouthwash used routinely for 5 days with the same duration and intensity. The data obtained was then analyzed with one-way analysis of variance followed by least significant difference. The level of significance was set as 0.05.
Plaque accumulation before and after dentifrice use significantly differed ( < 05) between the control and chitosan groups. The average reductions in plaque accumulation were greater in the chitosan group and control group brushing using chitosan-containing dentifrice.
Dentifrice-containing chitosan more effectively reduces dental plaque accumulation in patients with fixed orthodontic appliances than dentifrice without chitosan.
固定正畸患者在清洁牙齿和口腔时会遇到问题。牙菌斑容易积聚在钢丝、托槽以及粘结材料与托槽之间的表面。菌斑积聚增加了脱矿、龋齿和牙龈炎的风险。壳聚糖提取物是一种潜在的抗菌剂和牙菌斑形成抑制剂。本研究旨在评估含壳聚糖牙膏在减少固定正畸矫治器患者菌斑积聚方面的有效性。
这是一项前瞻性、随机、双盲研究，纳入了32例接受固定正畸治疗最后阶段的正畸矫治器患者样本（在考虑研究效能后随机分为对照组和壳聚糖组）。在使用牙膏5天内，根据O'Leary菌斑指数测量使用牙膏前后的菌斑积聚情况。患者被指导分别使用含壳聚糖牙膏和不含壳聚糖牙膏作为对照进行刷牙。使用含壳聚糖牙膏和不含壳聚糖牙膏作为对照之间的洗脱期为7天。每种漱口水常规使用5天，使用时间和强度相同。然后对获得的数据进行单因素方差分析，随后进行最小显著差异分析。显著性水平设定为0.05。
对照组和壳聚糖组使用牙膏前后的菌斑积聚情况存在显著差异（<0.05）。壳聚糖组和使用含壳聚糖牙膏刷牙的对照组菌斑积聚的平均减少量更大。
含壳聚糖的牙膏比不含壳聚糖的牙膏更有效地减少固定正畸矫治器患者的牙菌斑积聚。
